| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PMM0080 | coaD | PMM0080 | PMM0884 | Conserved hypothetical protein; Alternative locus ID: PMED4_00831. | Putative pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.930 |
| PMM0080 | dfp | PMM0080 | PMM0229 | Conserved hypothetical protein; Alternative locus ID: PMED4_00831. | Putative p-pantothenate cysteine ligase and p-pantothenenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.927 |
| PMM0080 | panC, | PMM0080 | PMM1590 | Conserved hypothetical protein; Alternative locus ID: PMED4_00831. | Putative bifunctional enzyme; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | 0.969 |
| PMM0881 | PMM0883 | PMM0881 | PMM0883 | Conserved hypothetical protein; Alternative locus ID: PMED4_09921. | Conserved hypothetical protein; Alternative locus ID: PMED4_09941. | 0.619 |
| PMM0881 | coaD | PMM0881 | PMM0884 | Conserved hypothetical protein; Alternative locus ID: PMED4_09921. | Putative pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.613 |
| PMM0881 | uvrC | PMM0881 | PMM0882 | Conserved hypothetical protein; Alternative locus ID: PMED4_09921. | Excinuclease ABC subunit C (UvrC); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.617 |
| PMM0883 | PMM0881 | PMM0883 | PMM0881 | Conserved hypothetical protein; Alternative locus ID: PMED4_09941. | Conserved hypothetical protein; Alternative locus ID: PMED4_09921. | 0.619 |
| PMM0883 | coaD | PMM0883 | PMM0884 | Conserved hypothetical protein; Alternative locus ID: PMED4_09941. | Putative pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.671 |
| PMM0883 | uvrC | PMM0883 | PMM0882 | Conserved hypothetical protein; Alternative locus ID: PMED4_09941. | Excinuclease ABC subunit C (UvrC); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.828 |
| PMM1059 | coaD | PMM1059 | PMM0884 | Conserved hypothetical protein; Has F-G-G motif of methylases; Alternative locus ID: PMED4_12051. | Putative pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.791 |
| coaD | PMM0080 | PMM0884 | PMM0080 | Putative pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Conserved hypothetical protein; Alternative locus ID: PMED4_00831. | 0.930 |
| coaD | PMM0881 | PMM0884 | PMM0881 | Putative pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Conserved hypothetical protein; Alternative locus ID: PMED4_09921. | 0.613 |
| coaD | PMM0883 | PMM0884 | PMM0883 | Putative pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Conserved hypothetical protein; Alternative locus ID: PMED4_09941. | 0.671 |
| coaD | PMM1059 | PMM0884 | PMM1059 | Putative pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Conserved hypothetical protein; Has F-G-G motif of methylases; Alternative locus ID: PMED4_12051. | 0.791 |
| coaD | coaE | PMM0884 | PMM0049 | Putative pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Putative dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.941 |
| coaD | dfp | PMM0884 | PMM0229 | Putative pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Putative p-pantothenate cysteine ligase and p-pantothenenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.939 |
| coaD | guaA | PMM0884 | PMM0037 | Putative pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Glutamine amidotransferase class-I:GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.619 |
| coaD | panC, | PMM0884 | PMM1590 | Putative pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Putative bifunctional enzyme; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | 0.598 |
| coaD | ribF | PMM0884 | PMM1273 | Putative pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Putative riboflavin kinase/FAD synthase; Citation: Gupta et al. (1999) FEMS Microbiol Lett 179:501-506; Alternative locus ID: PMED4_14391; Belongs to the ribF family. | 0.623 |
| coaD | uvrC | PMM0884 | PMM0882 | Putative pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Excinuclease ABC subunit C (UvrC); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.664 |