Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ureBUrease beta subunit; Citation: Palinska et al. (2000) Microbiology 146:3099-3107; Alternative locus ID: PMED4_10761; Belongs to the urease beta subunit family. (106 aa)    
Predicted Functional Partners:
ureC
Urease alpha subunit; Citation: Palinska et al. (2000) Microbiology 146:3099-3107; Alternative locus ID: PMED4_10751; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
 0.999
ureA
Urease gamma subunit; Citation: Palinska et al. (2000) Microbiology 146:3099-3107; Alternative locus ID: PMED4_10771; Belongs to the urease gamma subunit family.
 0.999
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.996
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.979
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
  
 0.977
ureE
Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
   
 0.953
glsF,
Ferredoxin-dependent glutamate synthase, Fd-GOGAT; Alternative locus ID: PMED4_17221.
      
 0.557
urtA
Putative urea ABC transporter, substrate binding protein; Putative NtcA binding site of form GTTN8TACN22TAN3T beginning 93 bases upstream of putative start point; Citation: Valladares, A, ML Montesinos, A. Herrero, E. Flores (2002) Mol. Microbiol. 43:703-715; Alternative locus ID: PMED4_10821.
     
 0.451
ntcA
Global nitrogen regulatory protein, CRP family of transcriptional regulators; Alternative locus ID: PMED4_02511.
      
 0.413
hupE
Putative hydrogenase accessory protein; Alternative locus ID: PMED4_12701.
  
  
 0.410
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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