STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureDUrease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (297 aa)    
Predicted Functional Partners:
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.999
ureB
Urease beta subunit; Citation: Palinska et al. (2000) Microbiology 146:3099-3107; Alternative locus ID: PMED4_10761; Belongs to the urease beta subunit family.
 
 
 0.992
ureE
Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.992
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.992
ureC
Urease alpha subunit; Citation: Palinska et al. (2000) Microbiology 146:3099-3107; Alternative locus ID: PMED4_10751; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
 
  
 0.974
ureA
Urease gamma subunit; Citation: Palinska et al. (2000) Microbiology 146:3099-3107; Alternative locus ID: PMED4_10771; Belongs to the urease gamma subunit family.
 
 
 0.968
urtA
Putative urea ABC transporter, substrate binding protein; Putative NtcA binding site of form GTTN8TACN22TAN3T beginning 93 bases upstream of putative start point; Citation: Valladares, A, ML Montesinos, A. Herrero, E. Flores (2002) Mol. Microbiol. 43:703-715; Alternative locus ID: PMED4_10821.
 
   
 0.754
urtE
Putative ATP-binding subunit of urea ABC transport system; Citation: Valladares, A, ML Montesinos, A. Herrero, E. Flores (2002) Mol. Microbiol. 43:703-715; Alternative locus ID: PMED4_10861.
 
  
 0.630
urtC
Putative membrane protein of urea ABC transport system; Citation: Valladares, A, ML Montesinos, A. Herrero, E. Flores (2002) Mol. Microbiol. 43:703-715; Alternative locus ID: PMED4_10841; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.617
urtB
Putative urea ABC transporter; Citation: Valladares, A, ML Montesinos, A. Herrero, E. Flores (2002) Mol. Microbiol. 43:703-715; Alternative locus ID: PMED4_10831; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.597
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.