STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PMM10124-hydroxybenzoyl-CoA thioesterase family active site; Alternative locus ID: PMED4_11421. (137 aa)    
Predicted Functional Partners:
ilvD
Dihydroxy-acid dehydratase; Alternative locus ID: PMED4_08591; Belongs to the IlvD/Edd family.
  
  
 0.768
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
   
  
 0.760
PMM0331
Putative aldehyde dehydrogenase; Alternative locus ID: PMED4_03381; Belongs to the aldehyde dehydrogenase family.
   
  
 0.759
ilvE
Putative Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
      
 0.759
fabI
Enoyl-[acyl-carrier-protein] reductase; Alternative locus ID: PMED4_02871.
      
 0.734
cad
Orn/Lys/Arg decarboxylases family 1; Possible assignment; Alternative locus ID: PMED4_12301.
      
 0.707
PMM1937
Conserved hypothetical protein; Alternative locus ID: PMED4_11431.
       0.699
PMM1936
Conserved hypothetical protein; Alternative locus ID: PMED4_11411.
       0.651
PMM1013
Conserved hypothetical; Alternative locus ID: PMED4_11441.
  
    0.641
PMM1014
Conserved hypothetical protein; Alternative locus ID: PMED4_11451.
  
    0.605
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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