| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PMM0411 | PMM1059 | PMM0411 | PMM1059 | Conserved hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Conserved hypothetical protein; Has F-G-G motif of methylases; Alternative locus ID: PMED4_12051. | 0.576 |
| PMM1053 | PMM1059 | PMM1053 | PMM1059 | Conserved hypothetical protein; Alternative locus ID: PMED4_11991; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Conserved hypothetical protein; Has F-G-G motif of methylases; Alternative locus ID: PMED4_12051. | 0.451 |
| PMM1053 | cytM | PMM1053 | PMM1057 | Conserved hypothetical protein; Alternative locus ID: PMED4_11991; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Cytochrome cM; Alternative locus ID: PMED4_12031. | 0.569 |
| PMM1053 | trmJ | PMM1053 | PMM1056 | Conserved hypothetical protein; Alternative locus ID: PMED4_11991; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Probable tRNA/rRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.579 |
| PMM1059 | PMM0411 | PMM1059 | PMM0411 | Conserved hypothetical protein; Has F-G-G motif of methylases; Alternative locus ID: PMED4_12051. | Conserved hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.576 |
| PMM1059 | PMM1053 | PMM1059 | PMM1053 | Conserved hypothetical protein; Has F-G-G motif of methylases; Alternative locus ID: PMED4_12051. | Conserved hypothetical protein; Alternative locus ID: PMED4_11991; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.451 |
| PMM1059 | PMM1626 | PMM1059 | PMM1626 | Conserved hypothetical protein; Has F-G-G motif of methylases; Alternative locus ID: PMED4_12051. | Conserved hypothetical protein; Alternative locus ID: PMED4_18361. | 0.442 |
| PMM1059 | coaD | PMM1059 | PMM0884 | Conserved hypothetical protein; Has F-G-G motif of methylases; Alternative locus ID: PMED4_12051. | Putative pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.791 |
| PMM1059 | cytM | PMM1059 | PMM1057 | Conserved hypothetical protein; Has F-G-G motif of methylases; Alternative locus ID: PMED4_12051. | Cytochrome cM; Alternative locus ID: PMED4_12031. | 0.504 |
| PMM1059 | guaB | PMM1059 | PMM1062 | Conserved hypothetical protein; Has F-G-G motif of methylases; Alternative locus ID: PMED4_12051. | Putative IMP dehydrogenase; Alternative locus ID: PMED4_12081. | 0.432 |
| PMM1059 | hisH | PMM1059 | PMM1060 | Conserved hypothetical protein; Has F-G-G motif of methylases; Alternative locus ID: PMED4_12051. | Glutamine amidotransferase class-I; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.816 |
| PMM1059 | rlmH | PMM1059 | PMM0935 | Conserved hypothetical protein; Has F-G-G motif of methylases; Alternative locus ID: PMED4_12051. | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.451 |
| PMM1059 | trmJ | PMM1059 | PMM1056 | Conserved hypothetical protein; Has F-G-G motif of methylases; Alternative locus ID: PMED4_12051. | Probable tRNA/rRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.507 |
| PMM1059 | trxA | PMM1059 | PMM1061 | Conserved hypothetical protein; Has F-G-G motif of methylases; Alternative locus ID: PMED4_12051. | Thioredoxin; Alternative locus ID: PMED4_12071; Belongs to the thioredoxin family. | 0.805 |
| PMM1626 | PMM1059 | PMM1626 | PMM1059 | Conserved hypothetical protein; Alternative locus ID: PMED4_18361. | Conserved hypothetical protein; Has F-G-G motif of methylases; Alternative locus ID: PMED4_12051. | 0.442 |
| coaD | PMM1059 | PMM0884 | PMM1059 | Putative pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Conserved hypothetical protein; Has F-G-G motif of methylases; Alternative locus ID: PMED4_12051. | 0.791 |
| cytM | PMM1053 | PMM1057 | PMM1053 | Cytochrome cM; Alternative locus ID: PMED4_12031. | Conserved hypothetical protein; Alternative locus ID: PMED4_11991; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.569 |
| cytM | PMM1059 | PMM1057 | PMM1059 | Cytochrome cM; Alternative locus ID: PMED4_12031. | Conserved hypothetical protein; Has F-G-G motif of methylases; Alternative locus ID: PMED4_12051. | 0.504 |
| cytM | guaB | PMM1057 | PMM1062 | Cytochrome cM; Alternative locus ID: PMED4_12031. | Putative IMP dehydrogenase; Alternative locus ID: PMED4_12081. | 0.467 |
| cytM | hisH | PMM1057 | PMM1060 | Cytochrome cM; Alternative locus ID: PMED4_12031. | Glutamine amidotransferase class-I; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.481 |