STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gldAPutative glycerol dehydrogenase; Alternative locus ID: PMED4_12331. (364 aa)    
Predicted Functional Partners:
todF
2-hydroxy-6-oxohepta-2,4-dienoate hydrolase; Alternative locus ID: PMED4_12321.
  
    0.844
clpC
ClpC; Regulatory subunit of ATP-dependent Clp protease; Alternative locus ID: PMED4_12341; Belongs to the ClpA/ClpB family.
  
    0.820
rpl17,
50S ribosomal protein L17; Alternative locus ID: PMED4_17441.
   
  
 0.586
PMM1089
Putative ribosomal-protein-alanine acetyltransferase; Alternative locus ID: PMED4_12351.
       0.573
atp1
Possible ATP synthase subunit 1; Alternative locus ID: PMED4_16661.
   
  
 0.524
gyrA
DNA gyrase/topoisomerase IV, subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-depend [...]
      
 0.517
ftsZ
Cell division protein FtsZ:Tubulin/FtsZ family; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
      
 0.482
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
       0.479
PMM0615
Possible nitrilase; Alternative locus ID: PMED4_06641.
      0.459
dacA
Conserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
  
    0.430
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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