| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BioB | F2J10.13 | PMM1093 | PMM1095 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Conserved hypothetical protein; Alternative locus ID: PMED4_12411. | 0.828 |
| BioB | PMM1089 | PMM1093 | PMM1089 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Putative ribosomal-protein-alanine acetyltransferase; Alternative locus ID: PMED4_12351. | 0.574 |
| BioB | PMM1094 | PMM1093 | PMM1094 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Conserved hypothetical protein; Alternative locus ID: PMED4_12401; Belongs to the UPF0176 family. | 0.828 |
| BioB | dacA | PMM1093 | PMM1091 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Conserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.829 |
| BioB | lysA | PMM1093 | PMM1090 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.795 |
| BioB | uppS | PMM1093 | PMM1092 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Undecaprenyl pyrophosphate synthetase (UPPS); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.829 |
| F2J10.13 | BioB | PMM1095 | PMM1093 | Conserved hypothetical protein; Alternative locus ID: PMED4_12411. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.828 |
| F2J10.13 | PMM1089 | PMM1095 | PMM1089 | Conserved hypothetical protein; Alternative locus ID: PMED4_12411. | Putative ribosomal-protein-alanine acetyltransferase; Alternative locus ID: PMED4_12351. | 0.490 |
| F2J10.13 | PMM1094 | PMM1095 | PMM1094 | Conserved hypothetical protein; Alternative locus ID: PMED4_12411. | Conserved hypothetical protein; Alternative locus ID: PMED4_12401; Belongs to the UPF0176 family. | 0.944 |
| F2J10.13 | dacA | PMM1095 | PMM1091 | Conserved hypothetical protein; Alternative locus ID: PMED4_12411. | Conserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.805 |
| F2J10.13 | lysA | PMM1095 | PMM1090 | Conserved hypothetical protein; Alternative locus ID: PMED4_12411. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.694 |
| F2J10.13 | uppS | PMM1095 | PMM1092 | Conserved hypothetical protein; Alternative locus ID: PMED4_12411. | Undecaprenyl pyrophosphate synthetase (UPPS); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.808 |
| PMM0278 | dacA | PMM0278 | PMM1091 | Phosphotransferase superclass; Alternative locus ID: PMED4_02831. | Conserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.484 |
| PMM1068 | dacA | PMM1068 | PMM1091 | Conserved hypothetical protein; Alternative locus ID: PMED4_12141. | Conserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.470 |
| PMM1089 | BioB | PMM1089 | PMM1093 | Putative ribosomal-protein-alanine acetyltransferase; Alternative locus ID: PMED4_12351. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.574 |
| PMM1089 | F2J10.13 | PMM1089 | PMM1095 | Putative ribosomal-protein-alanine acetyltransferase; Alternative locus ID: PMED4_12351. | Conserved hypothetical protein; Alternative locus ID: PMED4_12411. | 0.490 |
| PMM1089 | PMM1094 | PMM1089 | PMM1094 | Putative ribosomal-protein-alanine acetyltransferase; Alternative locus ID: PMED4_12351. | Conserved hypothetical protein; Alternative locus ID: PMED4_12401; Belongs to the UPF0176 family. | 0.577 |
| PMM1089 | clpC | PMM1089 | PMM1088 | Putative ribosomal-protein-alanine acetyltransferase; Alternative locus ID: PMED4_12351. | ClpC; Regulatory subunit of ATP-dependent Clp protease; Alternative locus ID: PMED4_12341; Belongs to the ClpA/ClpB family. | 0.588 |
| PMM1089 | dacA | PMM1089 | PMM1091 | Putative ribosomal-protein-alanine acetyltransferase; Alternative locus ID: PMED4_12351. | Conserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.615 |
| PMM1089 | lysA | PMM1089 | PMM1090 | Putative ribosomal-protein-alanine acetyltransferase; Alternative locus ID: PMED4_12351. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.679 |