Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pdxJPyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (238 aa)    
Predicted Functional Partners:
pdxA
Putative pyridoxal phosphate biosynthetic protein PdxA; Citation: Roa et al. (1989) J. Bacteriol. 171:4767-4777; Alternative locus ID: PMED4_00271; Belongs to the PdxA family.
 
 
 0.960
PMM1358
Conserved hypothetical protein; Alternative locus ID: PMED4_15261.
     
  0.900
cobD
Putative cobalamin biosynthetic protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
      
 0.881
PMM1106
Conserved hypothetical protein; Alternative locus ID: PMED4_12521.
       0.818
recC
Possible exodeoxyribonuclease V subunit C 125 kD polypeptide; Alternative locus ID: PMED4_12511.
       0.785
PMM1104
Conserved hypothetical protein; Alternative locus ID: PMED4_12501.
       0.780
recD
Possible exodeoxyribonuclease V 67 kD polypeptide; Alternative locus ID: PMED4_12481.
       0.767
recB
Possible UvrD/REP helicase subunit B; Alternative locus ID: PMED4_12491.
       0.767
era
GTP-binding protein ERA homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
    
 0.722
ribA/ribB
Possible GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.644
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.