Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (976 aa)    
Predicted Functional Partners:
recA
RecA bacterial DNA recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.973
PMM0679
Putative transcripton factor; Alternative locus ID: PMED4_07351.
   
 0.971
mutS,fdv
Putative DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity).
   
 0.949
PMM1564
Conserved hypothetical protein; Alternative locus ID: PMED4_17741.
   
 0.926
PMM0384
Possible uncharacterized restriction enzyme, interrupted-C; Alternative locus ID: PMED4_04231.
  
 0.918
holB
DNA polymerase III, delta prime subunit; Alternative locus ID: PMED4_01351.
  
 0.917
cysS
Cysteinyl-tRNA synthetase; Alternative locus ID: PMED4_12991; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.890
rnhB
Ribonuclease HII and HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
 
 0.873
PMM0729
Possible ATP-dependent DNA ligase; Alternative locus ID: PMED4_08061.
  
 0.872
lig
ATP-dependent DNA ligase; Alternative locus ID: PMED4_18901.
  
 0.872
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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