Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gmdGDPmannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (357 aa)    
Predicted Functional Partners:
fcl
Putative fucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
 0.997
manC
GDP-mannose pyrophosphorylase; Alternative locus ID: PMED4_13611; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
 0.970
PMM1216
Putative sugar-phosphate nucleotidyl transferase; Alternative locus ID: PMED4_13811.
  
 
 0.905
cugP
Putative sugar-phosphate nucleotidyl transferase; Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate.
    
 0.904
glmS
Glutamine--fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
     
 0.802
galE
UDP-glucose-4-epimerase; Alternative locus ID: PMED4_13741; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
  
  
 0.801
ugd
UDP-glucose 6-dehydrogenase; Alternative locus ID: PMED4_14271; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
  
  
 0.793
trxA
Thioredoxin; Alternative locus ID: PMED4_12071; Belongs to the thioredoxin family.
    
   0.738
rpl4,
50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
 
      0.719
PMM1225
Conserved hypothetical protein; Alternative locus ID: PMED4_13901.
  
  
 0.643
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.