| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PMM1229 | gcsH, | PMM1229 | PMM1669 | Dehydrogenase, E1 component; Alternative locus ID: PMED4_13941. | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.633 |
| PMM1229 | lpdA | PMM1229 | PMM1298 | Dehydrogenase, E1 component; Alternative locus ID: PMED4_13941. | Putative dihydrolipoamide dehydrogenase; Alternative locus ID: PMED4_14641. | 0.970 |
| PMM1229 | pdhA | PMM1229 | PMM1288 | Dehydrogenase, E1 component; Alternative locus ID: PMED4_13941. | Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.922 |
| PMM1229 | pdhB | PMM1229 | PMM0930 | Dehydrogenase, E1 component; Alternative locus ID: PMED4_13941. | Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.999 |
| PMM1229 | pdhC | PMM1229 | PMM0405 | Dehydrogenase, E1 component; Alternative locus ID: PMED4_13941. | Dihydrolipoamide acetyltransferase component (E2) of pyruvate de; Alternative locus ID: PMED4_04481. | 0.998 |
| gcsH, | PMM1229 | PMM1669 | PMM1229 | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dehydrogenase, E1 component; Alternative locus ID: PMED4_13941. | 0.633 |
| gcsH, | gcvP | PMM1669 | PMM1668 | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system P-protein; Alternative locus ID: PMED4_18781; Belongs to the GcvP family. | 0.999 |
| gcsH, | gcvT | PMM1669 | PMM1687 | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Putative Glycine cleavage T-protein (aminomethyl transferase); The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
| gcsH, | glnA | PMM1669 | PMM0920 | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glutamine synthetase, glutamate--ammonia ligase; Alternative locus ID: PMED4_10311. | 0.821 |
| gcsH, | glyA | PMM1669 | PMM0258 | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine hydroxymethyltransferase (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.989 |
| gcsH, | lpdA | PMM1669 | PMM1298 | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Putative dihydrolipoamide dehydrogenase; Alternative locus ID: PMED4_14641. | 0.987 |
| gcsH, | pdhA | PMM1669 | PMM1288 | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.635 |
| gcsH, | pdhB | PMM1669 | PMM0930 | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.669 |
| gcsH, | pdhC | PMM1669 | PMM0405 | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoamide acetyltransferase component (E2) of pyruvate de; Alternative locus ID: PMED4_04481. | 0.900 |
| gcsH, | spt, | PMM1669 | PMM0919 | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Class-V aminotransferase; Alternative locus ID: PMED4_10301. | 0.906 |
| gcvP | gcsH, | PMM1668 | PMM1669 | Glycine cleavage system P-protein; Alternative locus ID: PMED4_18781; Belongs to the GcvP family. | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
| gcvP | gcvT | PMM1668 | PMM1687 | Glycine cleavage system P-protein; Alternative locus ID: PMED4_18781; Belongs to the GcvP family. | Putative Glycine cleavage T-protein (aminomethyl transferase); The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
| gcvP | glnA | PMM1668 | PMM0920 | Glycine cleavage system P-protein; Alternative locus ID: PMED4_18781; Belongs to the GcvP family. | Glutamine synthetase, glutamate--ammonia ligase; Alternative locus ID: PMED4_10311. | 0.885 |
| gcvP | glyA | PMM1668 | PMM0258 | Glycine cleavage system P-protein; Alternative locus ID: PMED4_18781; Belongs to the GcvP family. | Serine hydroxymethyltransferase (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.999 |
| gcvP | lpdA | PMM1668 | PMM1298 | Glycine cleavage system P-protein; Alternative locus ID: PMED4_18781; Belongs to the GcvP family. | Putative dihydrolipoamide dehydrogenase; Alternative locus ID: PMED4_14641. | 0.955 |