| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dnaB | ftsZ | PMM1674 | PMM1309 | DnaB replicative helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Cell division protein FtsZ:Tubulin/FtsZ family; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.606 |
| dnaB | kaiB | PMM1674 | PMM1343 | DnaB replicative helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Possible circadian oscillation regulator KaiB; Probable component of the KaiBC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. In the complex, it may affect the phosphorylation status of KaiC. | 0.602 |
| dnaB | kaiC | PMM1674 | PMM1342 | DnaB replicative helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Possible circadian clock protein KaiC; Core component of the KaiBC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiBC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family. | 0.808 |
| dnaB | recA | PMM1674 | PMM1562 | DnaB replicative helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | RecA bacterial DNA recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.843 |
| ftsZ | dnaB | PMM1309 | PMM1674 | Cell division protein FtsZ:Tubulin/FtsZ family; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | DnaB replicative helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.606 |
| ftsZ | kaiB | PMM1309 | PMM1343 | Cell division protein FtsZ:Tubulin/FtsZ family; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Possible circadian oscillation regulator KaiB; Probable component of the KaiBC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. In the complex, it may affect the phosphorylation status of KaiC. | 0.671 |
| ftsZ | kaiC | PMM1309 | PMM1342 | Cell division protein FtsZ:Tubulin/FtsZ family; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Possible circadian clock protein KaiC; Core component of the KaiBC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiBC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family. | 0.800 |
| ftsZ | purF | PMM1309 | PMM0004 | Cell division protein FtsZ:Tubulin/FtsZ family; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Glutamine amidotransferase class-II:Phosphoribosyl transferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.503 |
| ftsZ | recA | PMM1309 | PMM1562 | Cell division protein FtsZ:Tubulin/FtsZ family; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | RecA bacterial DNA recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.848 |
| ftsZ | rnpA | PMM1309 | PMM1184 | Cell division protein FtsZ:Tubulin/FtsZ family; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Bacterial ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.410 |
| kaiB | dnaB | PMM1343 | PMM1674 | Possible circadian oscillation regulator KaiB; Probable component of the KaiBC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. In the complex, it may affect the phosphorylation status of KaiC. | DnaB replicative helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.602 |
| kaiB | ftsZ | PMM1343 | PMM1309 | Possible circadian oscillation regulator KaiB; Probable component of the KaiBC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. In the complex, it may affect the phosphorylation status of KaiC. | Cell division protein FtsZ:Tubulin/FtsZ family; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.671 |
| kaiB | kaiC | PMM1343 | PMM1342 | Possible circadian oscillation regulator KaiB; Probable component of the KaiBC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. In the complex, it may affect the phosphorylation status of KaiC. | Possible circadian clock protein KaiC; Core component of the KaiBC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiBC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family. | 0.999 |
| kaiB | purF | PMM1343 | PMM0004 | Possible circadian oscillation regulator KaiB; Probable component of the KaiBC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. In the complex, it may affect the phosphorylation status of KaiC. | Glutamine amidotransferase class-II:Phosphoribosyl transferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.778 |
| kaiB | recA | PMM1343 | PMM1562 | Possible circadian oscillation regulator KaiB; Probable component of the KaiBC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. In the complex, it may affect the phosphorylation status of KaiC. | RecA bacterial DNA recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.813 |
| kaiB | rnpA | PMM1343 | PMM1184 | Possible circadian oscillation regulator KaiB; Probable component of the KaiBC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. In the complex, it may affect the phosphorylation status of KaiC. | Bacterial ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.513 |
| kaiB | rpaB | PMM1343 | PMM0134 | Possible circadian oscillation regulator KaiB; Probable component of the KaiBC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. In the complex, it may affect the phosphorylation status of KaiC. | Two-component response regulator; Alternative locus ID: PMED4_01401. | 0.742 |
| kaiB | rpl21, | PMM1343 | PMM1344 | Possible circadian oscillation regulator KaiB; Probable component of the KaiBC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. In the complex, it may affect the phosphorylation status of KaiC. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.931 |
| kaiB | rpl27, | PMM1343 | PMM1345 | Possible circadian oscillation regulator KaiB; Probable component of the KaiBC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. In the complex, it may affect the phosphorylation status of KaiC. | 50S ribosomal protein L27; Alternative locus ID: PMED4_15131; Belongs to the bacterial ribosomal protein bL27 family. | 0.615 |
| kaiB | thiE | PMM1343 | PMM1274 | Possible circadian oscillation regulator KaiB; Probable component of the KaiBC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. In the complex, it may affect the phosphorylation status of KaiC. | Thiamine monophosphate synthase (TMP); Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | 0.734 |