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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cobHPutative Precorrin-8X methylmutase CobH; Citation: Thibaut et al. (1992) J. Bacteriol. 174:1043-1049; Alternative locus ID: PMED4_18561. (207 aa)    
Predicted Functional Partners:
cobL
Putative precorrin-6y methylase; Citation: Blanche et al. (1992) J. Bacteriol. 174:1050-1052; Alternative locus ID: PMED4_14341.
 
 
 0.999
cbiG/cobJ
Bifunctional cbiH protien and PRECORRIN-3B C17-METHYLTRANSFERASE; Citation: Debussche et al. (1993) J. Bacteriol. 175:7430-7440; Roth et al. (1993) J. Bacteriol. 175:3303-3316; Alternative locus ID: PMED4_17351.
  
 0.998
cbiA,cobB
Putative Cobyrinic acid a,c-diamide synthase; BELONGS TO THE SIRTUIN FAMILY; Citation: Tsang and Escalante-Semerena (1996) J. Bacteriol. 178:7016-7019; Alternative locus ID: PMED4_12181.
 
 0.996
cobB
Cobyric acid synthase CobB; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.984
cobI/cbiL
PRECORRIN-2 C20-METHYLTRANSFERASE; Cobalamin biosynthesis; Citation: Crouzet et al. (1990) J. Bacteriol. 172:5980-5990; Roth et al. (1993) J. Bacteriol. 175:3303-3316; Alternative locus ID: PMED4_04301; Belongs to the precorrin methyltransferase family.
 
  
 0.978
cobM
PUTATIVE PRECORRIN-4 C11-METHYLTRANSFERASE; Citation: Crouzet et al. (1990) J. Bacteriol. 172:5980-5990; Debussche et al. (1993) J. Bacteriol. 175:7430-7440; Alternative locus ID: PMED4_05071.
 
  
 0.978
PMM0503
Possible precorrin-6X reductase; Alternative locus ID: PMED4_05521.
 
  
 0.962
PMM0646
Conserved hypothetical protein; Alternative locus ID: PMED4_06961.
   
 0.955
CobN
Cobalamin biosynthetic protein CobN; Citation: Crouzet et al. (1991) J. Bacteriol. 173:6074-6087; Alternative locus ID: PMED4_09901.
 
  
 0.937
cbiD
CbiD protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.913
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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