STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiGThiamin biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (265 aa)    
Predicted Functional Partners:
thiO
PUTATIVE THIAMINE BIOSYNTHESIS OXIDOREDUCTASE; Citation: Mirand-Rios et al. (1997) J. Bacteriol. 179:6887-6893; Alternative locus ID: PMED4_00471.
 
 0.999
moeB
Molybdopterin biosynthesis protein; BELONGS TO THE HESA/MOEB/THIF FAMILY; Citation: Nohno et al (1988) J. Bacteriol. 170:4097-4102; Alternative locus ID: PMED4_17791.
  
 0.994
PMM1275
DUF170; Alternative locus ID: PMED4_14411.
  
 
 0.992
thiC
ThiC family; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
 
  
 0.969
thiE
Thiamine monophosphate synthase (TMP); Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
  
 0.958
thiD
Phosphomethylpyrimidine kinase; Citation: Peterson and Downs (1997) J. Bacteriol. 179:4894-4900; Alternative locus ID: PMED4_03821.
  
  
 0.947
Dxs
1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
   
 
 0.928
PMM1663
Putative photosystem I assembly related protein Ycf37; Alternative locus ID: PMED4_18731.
  
    0.829
rpl20,
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
       0.731
rpl35,
50S ribosomal protein L35; Alternative locus ID: PMED4_18711; Belongs to the bacterial ribosomal protein bL35 family.
       0.669
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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