| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PMM0539 | gcsH, | PMM0539 | PMM1669 | Biotin/lipoate A/B protein ligase family; Alternative locus ID: PMED4_05881. | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.951 |
| PMM0539 | gcvT | PMM0539 | PMM1687 | Biotin/lipoate A/B protein ligase family; Alternative locus ID: PMED4_05881. | Putative Glycine cleavage T-protein (aminomethyl transferase); The glycine cleavage system catalyzes the degradation of glycine. | 0.432 |
| PMM0539 | lipB | PMM0539 | PMM0401 | Biotin/lipoate A/B protein ligase family; Alternative locus ID: PMED4_05881. | Putative lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.989 |
| PMM0539 | lpdA | PMM0539 | PMM1298 | Biotin/lipoate A/B protein ligase family; Alternative locus ID: PMED4_05881. | Putative dihydrolipoamide dehydrogenase; Alternative locus ID: PMED4_14641. | 0.723 |
| PMM0539 | pdhC | PMM0539 | PMM0405 | Biotin/lipoate A/B protein ligase family; Alternative locus ID: PMED4_05881. | Dihydrolipoamide acetyltransferase component (E2) of pyruvate de; Alternative locus ID: PMED4_04481. | 0.881 |
| PMM1671 | gcsH, | PMM1671 | PMM1669 | Conserved hypothetical protein; Alternative locus ID: PMED4_18811. | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.829 |
| PMM1671 | gcvP | PMM1671 | PMM1668 | Conserved hypothetical protein; Alternative locus ID: PMED4_18811. | Glycine cleavage system P-protein; Alternative locus ID: PMED4_18781; Belongs to the GcvP family. | 0.715 |
| acpP,acp | gcsH, | PMM1608 | PMM1669 | Acyl carrier protein (ACP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.885 |
| acpP,acp | lipB | PMM1608 | PMM0401 | Acyl carrier protein (ACP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | Putative lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.966 |
| acpP,acp | pdhC | PMM1608 | PMM0405 | Acyl carrier protein (ACP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | Dihydrolipoamide acetyltransferase component (E2) of pyruvate de; Alternative locus ID: PMED4_04481. | 0.424 |
| gcsH, | PMM0539 | PMM1669 | PMM0539 | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Biotin/lipoate A/B protein ligase family; Alternative locus ID: PMED4_05881. | 0.951 |
| gcsH, | PMM1671 | PMM1669 | PMM1671 | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Conserved hypothetical protein; Alternative locus ID: PMED4_18811. | 0.829 |
| gcsH, | acpP,acp | PMM1669 | PMM1608 | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Acyl carrier protein (ACP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.885 |
| gcsH, | gcvP | PMM1669 | PMM1668 | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system P-protein; Alternative locus ID: PMED4_18781; Belongs to the GcvP family. | 0.999 |
| gcsH, | gcvT | PMM1669 | PMM1687 | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Putative Glycine cleavage T-protein (aminomethyl transferase); The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
| gcsH, | glyA | PMM1669 | PMM0258 | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine hydroxymethyltransferase (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.989 |
| gcsH, | lipB | PMM1669 | PMM0401 | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Putative lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.916 |
| gcsH, | lpdA | PMM1669 | PMM1298 | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Putative dihydrolipoamide dehydrogenase; Alternative locus ID: PMED4_14641. | 0.987 |
| gcsH, | pdhC | PMM1669 | PMM0405 | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoamide acetyltransferase component (E2) of pyruvate de; Alternative locus ID: PMED4_04481. | 0.900 |
| gcsH, | spt, | PMM1669 | PMM0919 | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Class-V aminotransferase; Alternative locus ID: PMED4_10301. | 0.906 |