Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
queCHypothetical ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (224 aa)    
Predicted Functional Partners:
queE
Possible organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
 
 0.999
queF
Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
 
 
 0.998
queA
Queuosine biosynthesis protein; Synthesizes oQ from preQ1 in a single S-adenosylmethionine- requiring step. The ribosyl moiety of AdoMet is transferred and isomerized to the epoxycyclopentane residue of oQ (By similarity). Belongs to the QueA family.
     
 0.934
PMM1693
Aminotransferases class-IV; Hypothetical aminotransferase; Alternative locus ID: PMED4_19041.
  
    0.824
PMM1692
Possible p-aminobenzoate synthetase; Citation: Goncharodd and Nichols (1984) J. Bacteriol. 159:57-62; Alternative locus ID: PMED4_19031.
       0.818
dnaX
DNA polymerase, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
  
 0.804
PMM0106
6-pyruvoyl tetrahydropterin synthase; Alternative locus ID: PMED4_01121.
  
  
 0.781
PMM0579
Conserved hypothetical protein; Alternative locus ID: PMED4_06281.
  
  
 0.781
pyrG
Glutamine amidotransferase class-I:CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
       0.745
folE
Putative GTP cyclohydrolase I; Citation: Katzenmeier et al. (1991) Biol. Chem. Hoppe-Seyler 372:991-997; Alternative locus ID: PMED4_05851.
     
 0.702
Your Current Organism:
Prochlorococcus marinus pastoris
NCBI taxonomy Id: 59919
Other names: P. marinus subsp. pastoris str. CCMP1986, Prochlorococcus marinus MED4, Prochlorococcus marinus subsp. pastoris str. CCMP1378, Prochlorococcus marinus subsp. pastoris str. CCMP1986, Prochlorococcus sp. CCMP1378, Prochlorococcus sp. MED4
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