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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (315 aa)    
Predicted Functional Partners:
AAZ58193.1
Homoserine dehydrogenase; Alternative locus ID: NATL2_14771.
 
 0.996
AAZ58816.1
L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
 
 0.995
purM
Phosphoribosylformylglycinamidine cyclo-ligase; Alternative locus ID: NATL2_19861.
 
    
 0.906
AAZ57825.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.900
AAZ59230.1
Cystathionine gamma-synthase; Alternative locus ID: NATL2_04431.
  
 
 0.839
AAZ59231.1
Cystathionine gamma-synthase; Alternative locus ID: NATL2_04441.
  
 
 0.839
ilvE
Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.832
AAZ58707.1
Serine O-acetyltransferase; Alternative locus ID: NATL2_20391.
     
 0.832
AAZ58785.1
Aminotransferases class-IV; Alternative locus ID: NATL2_21221.
  
 
 0.832
AAZ57575.1
O-acetylhomoserine sulfhydrolase; Alternative locus ID: NATL2_06881.
    
  0.811
Your Current Organism:
Prochlorococcus marinus NATL2A
NCBI taxonomy Id: 59920
Other names: P. marinus str. NATL2A, Prochlorococcus marinus str. NATL2A, Prochlorococcus sp. NATL2A
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