| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AAZ58179.1 | AAZ58181.1 | PMN2A_0688 | PMN2A_0690 | Lycopene cyclase (CrtL-type); Alternative locus ID: NATL2_14611. | IMP dehydrogenase related 2; Alternative locus ID: NATL2_14631. | 0.555 |
| AAZ58179.1 | gyrA | PMN2A_0688 | PMN2A_0689 | Lycopene cyclase (CrtL-type); Alternative locus ID: NATL2_14611. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.818 |
| AAZ58181.1 | AAZ58179.1 | PMN2A_0690 | PMN2A_0688 | IMP dehydrogenase related 2; Alternative locus ID: NATL2_14631. | Lycopene cyclase (CrtL-type); Alternative locus ID: NATL2_14611. | 0.555 |
| AAZ58181.1 | guaA | PMN2A_0690 | PMN2A_1363 | IMP dehydrogenase related 2; Alternative locus ID: NATL2_14631. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.968 |
| AAZ58181.1 | gyrA | PMN2A_0690 | PMN2A_0689 | IMP dehydrogenase related 2; Alternative locus ID: NATL2_14631. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.581 |
| AAZ59111.1 | gyrA | PMN2A_1623 | PMN2A_0689 | Competence/damage-inducible protein cinA; Alternative locus ID: NATL2_03151; Belongs to the CinA family. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.504 |
| AAZ59111.1 | gyrB | PMN2A_1623 | PMN2A_1213 | Competence/damage-inducible protein cinA; Alternative locus ID: NATL2_03151; Belongs to the CinA family. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.519 |
| AAZ59111.1 | polA | PMN2A_1623 | PMN2A_0748 | Competence/damage-inducible protein cinA; Alternative locus ID: NATL2_03151; Belongs to the CinA family. | DNA polymerase A; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.623 |
| AAZ59334.1 | gyrA | PMN2A_1846 | PMN2A_0689 | Signal peptidase I, Serine peptidase, MEROPS family S26A; Alternative locus ID: NATL2_05531; Belongs to the peptidase S26 family. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.574 |
| AAZ59334.1 | tuf | PMN2A_1846 | PMN2A_1074 | Signal peptidase I, Serine peptidase, MEROPS family S26A; Alternative locus ID: NATL2_05531; Belongs to the peptidase S26 family. | Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.735 |
| guaA | AAZ58181.1 | PMN2A_1363 | PMN2A_0690 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | IMP dehydrogenase related 2; Alternative locus ID: NATL2_14631. | 0.968 |
| guaA | gyrA | PMN2A_1363 | PMN2A_0689 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.474 |
| guaA | gyrB | PMN2A_1363 | PMN2A_1213 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.538 |
| guaA | pheT | PMN2A_1363 | PMN2A_0338 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | phenylalanyl-tRNA synthetase beta subunit; Alternative locus ID: NATL2_09581; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.924 |
| guaA | polA | PMN2A_1363 | PMN2A_0748 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | DNA polymerase A; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.668 |
| guaA | rplD | PMN2A_1363 | PMN2A_1128 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | LSU ribosomal protein L4P; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.439 |
| guaA | tuf | PMN2A_1363 | PMN2A_1074 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.974 |
| gyrA | AAZ58179.1 | PMN2A_0689 | PMN2A_0688 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Lycopene cyclase (CrtL-type); Alternative locus ID: NATL2_14611. | 0.818 |
| gyrA | AAZ58181.1 | PMN2A_0689 | PMN2A_0690 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | IMP dehydrogenase related 2; Alternative locus ID: NATL2_14631. | 0.581 |
| gyrA | AAZ59111.1 | PMN2A_0689 | PMN2A_1623 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Competence/damage-inducible protein cinA; Alternative locus ID: NATL2_03151; Belongs to the CinA family. | 0.504 |
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