| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AAZ57825.1 | AAZ58193.1 | PMN2A_0333 | PMN2A_0702 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine dehydrogenase; Alternative locus ID: NATL2_14771. | 0.933 |
| AAZ57825.1 | AAZ58785.1 | PMN2A_0333 | PMN2A_1295 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aminotransferases class-IV; Alternative locus ID: NATL2_21221. | 0.506 |
| AAZ57825.1 | AAZ58816.1 | PMN2A_0333 | PMN2A_1327 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.544 |
| AAZ57825.1 | AAZ59230.1 | PMN2A_0333 | PMN2A_1742 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine gamma-synthase; Alternative locus ID: NATL2_04431. | 0.974 |
| AAZ57825.1 | AAZ59231.1 | PMN2A_0333 | PMN2A_1743 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine gamma-synthase; Alternative locus ID: NATL2_04441. | 0.974 |
| AAZ57825.1 | asd | PMN2A_0333 | PMN2A_1252 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.544 |
| AAZ57825.1 | ilvE | PMN2A_0333 | PMN2A_0332 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.797 |
| AAZ57825.1 | metAA | PMN2A_0333 | PMN2A_0084 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.790 |
| AAZ57825.1 | thrB | PMN2A_0333 | PMN2A_0031 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.900 |
| AAZ58193.1 | AAZ57825.1 | PMN2A_0702 | PMN2A_0333 | Homoserine dehydrogenase; Alternative locus ID: NATL2_14771. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.933 |
| AAZ58193.1 | AAZ58785.1 | PMN2A_0702 | PMN2A_1295 | Homoserine dehydrogenase; Alternative locus ID: NATL2_14771. | Aminotransferases class-IV; Alternative locus ID: NATL2_21221. | 0.862 |
| AAZ58193.1 | AAZ58816.1 | PMN2A_0702 | PMN2A_1327 | Homoserine dehydrogenase; Alternative locus ID: NATL2_14771. | L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.964 |
| AAZ58193.1 | AAZ59230.1 | PMN2A_0702 | PMN2A_1742 | Homoserine dehydrogenase; Alternative locus ID: NATL2_14771. | Cystathionine gamma-synthase; Alternative locus ID: NATL2_04431. | 0.869 |
| AAZ58193.1 | AAZ59231.1 | PMN2A_0702 | PMN2A_1743 | Homoserine dehydrogenase; Alternative locus ID: NATL2_14771. | Cystathionine gamma-synthase; Alternative locus ID: NATL2_04441. | 0.869 |
| AAZ58193.1 | asd | PMN2A_0702 | PMN2A_1252 | Homoserine dehydrogenase; Alternative locus ID: NATL2_14771. | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.970 |
| AAZ58193.1 | dapA | PMN2A_0702 | PMN2A_1251 | Homoserine dehydrogenase; Alternative locus ID: NATL2_14771. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.949 |
| AAZ58193.1 | ilvE | PMN2A_0702 | PMN2A_0332 | Homoserine dehydrogenase; Alternative locus ID: NATL2_14771. | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.862 |
| AAZ58193.1 | metAA | PMN2A_0702 | PMN2A_0084 | Homoserine dehydrogenase; Alternative locus ID: NATL2_14771. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.936 |
| AAZ58193.1 | thrB | PMN2A_0702 | PMN2A_0031 | Homoserine dehydrogenase; Alternative locus ID: NATL2_14771. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.996 |
| AAZ58785.1 | AAZ57825.1 | PMN2A_1295 | PMN2A_0333 | Aminotransferases class-IV; Alternative locus ID: NATL2_21221. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.506 |