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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadENAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (569 aa)    
Predicted Functional Partners:
AAZ58466.1
Putative nicotinate-nucleotide adenylyltransferase; Alternative locus ID: NATL2_17871; Belongs to the NadD family.
  
 
 0.989
nadK1
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.949
nadK2
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.949
AAZ58244.1
Putative nicotinamide nucleotide transhydrogenase, subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.937
AAZ58245.1
NAD/NADP transhydrogenase alpha subunit; Alternative locus ID: NATL2_15331.
     
 0.905
AAZ58246.1
NAD/NADP transhydrogenase alpha subunit; Alternative locus ID: NATL2_15341.
     
 0.905
AAZ58464.1
Membrane associated SBC domains; Alternative locus ID: NATL2_17851.
       0.821
AAZ58465.1
Small GTP-binding protein domain; Alternative locus ID: NATL2_17861.
       0.821
AAZ58463.1
Aminopeptidase P, Metallo peptidase, MEROPS family M24B; Alternative locus ID: NATL2_17841; Belongs to the peptidase M24B family.
  
 
  0.682
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
   
 
 0.679
Your Current Organism:
Prochlorococcus marinus NATL2A
NCBI taxonomy Id: 59920
Other names: P. marinus str. NATL2A, Prochlorococcus marinus str. NATL2A, Prochlorococcus sp. NATL2A
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