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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (477 aa)    
Predicted Functional Partners:
AAZ57825.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.953
AAZ59230.1
Cystathionine gamma-synthase; Alternative locus ID: NATL2_04431.
  
 0.919
AAZ59231.1
Cystathionine gamma-synthase; Alternative locus ID: NATL2_04441.
  
 0.919
AAZ57575.1
O-acetylhomoserine sulfhydrolase; Alternative locus ID: NATL2_06881.
     
 0.916
AAZ58978.1
Cysteine synthase; Alternative locus ID: NATL2_01751; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.846
AAZ59229.1
Cysteine synthase; Alternative locus ID: NATL2_04421; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.846
ilvA
L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 
 0.830
AAZ58193.1
Homoserine dehydrogenase; Alternative locus ID: NATL2_14771.
   
 
  0.811
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
     
  0.800
AAZ58691.1
DedA family; Alternative locus ID: NATL2_20231.
       0.768
Your Current Organism:
Prochlorococcus marinus NATL2A
NCBI taxonomy Id: 59920
Other names: P. marinus str. NATL2A, Prochlorococcus marinus str. NATL2A, Prochlorococcus sp. NATL2A
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