| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AAZ58193.1 | AAZ58707.1 | PMN2A_0702 | PMN2A_1217 | Homoserine dehydrogenase; Alternative locus ID: NATL2_14771. | Serine O-acetyltransferase; Alternative locus ID: NATL2_20391. | 0.813 |
| AAZ58193.1 | ilvA | PMN2A_0702 | PMN2A_0299 | Homoserine dehydrogenase; Alternative locus ID: NATL2_14771. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.555 |
| AAZ58193.1 | thrB | PMN2A_0702 | PMN2A_0031 | Homoserine dehydrogenase; Alternative locus ID: NATL2_14771. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.996 |
| AAZ58706.1 | AAZ58707.1 | PMN2A_1216 | PMN2A_1217 | Transcriptional regulator, GntR family; Alternative locus ID: NATL2_20381. | Serine O-acetyltransferase; Alternative locus ID: NATL2_20391. | 0.821 |
| AAZ58707.1 | AAZ58193.1 | PMN2A_1217 | PMN2A_0702 | Serine O-acetyltransferase; Alternative locus ID: NATL2_20391. | Homoserine dehydrogenase; Alternative locus ID: NATL2_14771. | 0.813 |
| AAZ58707.1 | AAZ58706.1 | PMN2A_1217 | PMN2A_1216 | Serine O-acetyltransferase; Alternative locus ID: NATL2_20391. | Transcriptional regulator, GntR family; Alternative locus ID: NATL2_20381. | 0.821 |
| AAZ58707.1 | AAZ58978.1 | PMN2A_1217 | PMN2A_1490 | Serine O-acetyltransferase; Alternative locus ID: NATL2_20391. | Cysteine synthase; Alternative locus ID: NATL2_01751; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.978 |
| AAZ58707.1 | AAZ59229.1 | PMN2A_1217 | PMN2A_1741 | Serine O-acetyltransferase; Alternative locus ID: NATL2_20391. | Cysteine synthase; Alternative locus ID: NATL2_04421; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.975 |
| AAZ58707.1 | cysS | PMN2A_1217 | PMN2A_0749 | Serine O-acetyltransferase; Alternative locus ID: NATL2_20391. | cysteinyl-tRNA synthetase; Alternative locus ID: NATL2_15281; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.970 |
| AAZ58707.1 | glyA | PMN2A_1217 | PMN2A_1624 | Serine O-acetyltransferase; Alternative locus ID: NATL2_20391. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.845 |
| AAZ58707.1 | ilvA | PMN2A_1217 | PMN2A_0299 | Serine O-acetyltransferase; Alternative locus ID: NATL2_20391. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.807 |
| AAZ58707.1 | thrB | PMN2A_1217 | PMN2A_0031 | Serine O-acetyltransferase; Alternative locus ID: NATL2_20391. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.832 |
| AAZ58707.1 | trpA | PMN2A_1217 | PMN2A_0008 | Serine O-acetyltransferase; Alternative locus ID: NATL2_20391. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.809 |
| AAZ58707.1 | trpB | PMN2A_1217 | PMN2A_1531 | Serine O-acetyltransferase; Alternative locus ID: NATL2_20391. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.807 |
| AAZ58978.1 | AAZ58707.1 | PMN2A_1490 | PMN2A_1217 | Cysteine synthase; Alternative locus ID: NATL2_01751; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Serine O-acetyltransferase; Alternative locus ID: NATL2_20391. | 0.978 |
| AAZ58978.1 | AAZ59229.1 | PMN2A_1490 | PMN2A_1741 | Cysteine synthase; Alternative locus ID: NATL2_01751; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Cysteine synthase; Alternative locus ID: NATL2_04421; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.904 |
| AAZ58978.1 | cysS | PMN2A_1490 | PMN2A_0749 | Cysteine synthase; Alternative locus ID: NATL2_01751; Belongs to the cysteine synthase/cystathionine beta- synthase family. | cysteinyl-tRNA synthetase; Alternative locus ID: NATL2_15281; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.658 |
| AAZ59229.1 | AAZ58707.1 | PMN2A_1741 | PMN2A_1217 | Cysteine synthase; Alternative locus ID: NATL2_04421; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Serine O-acetyltransferase; Alternative locus ID: NATL2_20391. | 0.975 |
| AAZ59229.1 | AAZ58978.1 | PMN2A_1741 | PMN2A_1490 | Cysteine synthase; Alternative locus ID: NATL2_04421; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Cysteine synthase; Alternative locus ID: NATL2_01751; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.904 |
| AAZ59229.1 | cysS | PMN2A_1741 | PMN2A_0749 | Cysteine synthase; Alternative locus ID: NATL2_04421; Belongs to the cysteine synthase/cystathionine beta- synthase family. | cysteinyl-tRNA synthetase; Alternative locus ID: NATL2_15281; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.682 |