def protein (Prochlorococcus marinus NATL2A)

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def

Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (202 aa)

Predicted Functional Partners:

fmt

0.950

rplV

0.907

rpsT

0.875

rplU

0.869

tig

0.868

rpmA

0.865

rpsU

0.860

rplT

0.860

rplQ

0.856

rpsJ

0.850

Your Current Organism:

Prochlorococcus marinus NATL2A

NCBI taxonomy Id: 59920
Other names: P. marinus str. NATL2A, Prochlorococcus marinus str. NATL2A, Prochlorococcus sp. NATL2A

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node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
def	fmt	PMN2A_1431	PMN2A_0366	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.	0.950
def	rplQ	PMN2A_1431	PMN2A_1105	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	LSU ribosomal protein L17P; Alternative locus ID: NATL2_19271.	0.856
def	rplT	PMN2A_1431	PMN2A_1260	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.860
def	rplU	PMN2A_1431	PMN2A_0915	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.869
def	rplV	PMN2A_1431	PMN2A_1124	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	LSU ribosomal protein L22P; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).	0.907
def	rpmA	PMN2A_1431	PMN2A_0916	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	LSU ribosomal protein L27P; Alternative locus ID: NATL2_17151; Belongs to the bacterial ribosomal protein bL27 family.	0.865
def	rpsJ	PMN2A_1431	PMN2A_1073	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.850
def	rpsT	PMN2A_1431	PMN2A_1018	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	SSU ribosomal protein S20P; Binds directly to 16S ribosomal RNA.	0.875
def	rpsU	PMN2A_1431	PMN2A_1060	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	SSU ribosomal protein S21P; Alternative locus ID: NATL2_18761; Belongs to the bacterial ribosomal protein bS21 family.	0.860
def	tig	PMN2A_1431	PMN2A_1253	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.868
fmt	def	PMN2A_0366	PMN2A_1431	methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.950
rplQ	def	PMN2A_1105	PMN2A_1431	LSU ribosomal protein L17P; Alternative locus ID: NATL2_19271.	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.856
rplQ	rplT	PMN2A_1105	PMN2A_1260	LSU ribosomal protein L17P; Alternative locus ID: NATL2_19271.	LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.996
rplQ	rplU	PMN2A_1105	PMN2A_0915	LSU ribosomal protein L17P; Alternative locus ID: NATL2_19271.	LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.994
rplQ	rplV	PMN2A_1105	PMN2A_1124	LSU ribosomal protein L17P; Alternative locus ID: NATL2_19271.	LSU ribosomal protein L22P; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).	0.997
rplQ	rpmA	PMN2A_1105	PMN2A_0916	LSU ribosomal protein L17P; Alternative locus ID: NATL2_19271.	LSU ribosomal protein L27P; Alternative locus ID: NATL2_17151; Belongs to the bacterial ribosomal protein bL27 family.	0.994
rplQ	rpsJ	PMN2A_1105	PMN2A_1073	LSU ribosomal protein L17P; Alternative locus ID: NATL2_19271.	SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.997
rplQ	rpsT	PMN2A_1105	PMN2A_1018	LSU ribosomal protein L17P; Alternative locus ID: NATL2_19271.	SSU ribosomal protein S20P; Binds directly to 16S ribosomal RNA.	0.983
rplQ	rpsU	PMN2A_1105	PMN2A_1060	LSU ribosomal protein L17P; Alternative locus ID: NATL2_19271.	SSU ribosomal protein S21P; Alternative locus ID: NATL2_18761; Belongs to the bacterial ribosomal protein bS21 family.	0.967
rplQ	tig	PMN2A_1105	PMN2A_1253	LSU ribosomal protein L17P; Alternative locus ID: NATL2_19271.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.910

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