Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AAZ58963.16-pyruvoyl-tetrahydropterin synthase-like protein; Alternative locus ID: NATL2_01591. (308 aa)    
Predicted Functional Partners:
queE
Possible organic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
  
 
 0.972
AAZ58517.1
GTP cyclohydrolase I; Alternative locus ID: NATL2_18391.
  
 
 0.938
AAZ57507.1
Conserved hypothetical protein; Alternative locus ID: NATL2_06181.
     
  0.900
AAZ58962.1
Pyrimidine reductase; Alternative locus ID: NATL2_01581.
 
     0.839
AAZ58961.1
Conserved hypothetical protein; Alternative locus ID: NATL2_01571.
       0.764
queC
preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
  
  
 0.762
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
       0.643
AAZ58960.1
Hypothetical protein; Alternative locus ID: NATL2_01561.
       0.637
AAZ57501.1
Uncharacterized YCII family conserved protein; Alternative locus ID: NATL2_06111.
  
     0.631
queF
GTP cyclohydrolase I family enzyme; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
  
  
 0.604
Your Current Organism:
Prochlorococcus marinus NATL2A
NCBI taxonomy Id: 59920
Other names: P. marinus str. NATL2A, Prochlorococcus marinus str. NATL2A, Prochlorococcus sp. NATL2A
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