| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AAZ58260.1 | AAZ59212.1 | PMN2A_0769 | PMN2A_1724 | Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Dihydrouridine synthase TIM-barrel protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.524 |
| AAZ58821.1 | AAZ59212.1 | PMN2A_1332 | PMN2A_1724 | DNA topoisomerase IV subunit A; Alternative locus ID: NATL2_00041. | Dihydrouridine synthase TIM-barrel protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.413 |
| AAZ58821.1 | guaA | PMN2A_1332 | PMN2A_1363 | DNA topoisomerase IV subunit A; Alternative locus ID: NATL2_00041. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.474 |
| AAZ58821.1 | gyrB | PMN2A_1332 | PMN2A_1213 | DNA topoisomerase IV subunit A; Alternative locus ID: NATL2_00041. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.983 |
| AAZ58821.1 | pheT | PMN2A_1332 | PMN2A_0338 | DNA topoisomerase IV subunit A; Alternative locus ID: NATL2_00041. | phenylalanyl-tRNA synthetase beta subunit; Alternative locus ID: NATL2_09581; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.653 |
| AAZ59212.1 | AAZ58260.1 | PMN2A_1724 | PMN2A_0769 | Dihydrouridine synthase TIM-barrel protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.524 |
| AAZ59212.1 | AAZ58821.1 | PMN2A_1724 | PMN2A_1332 | Dihydrouridine synthase TIM-barrel protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | DNA topoisomerase IV subunit A; Alternative locus ID: NATL2_00041. | 0.413 |
| AAZ59212.1 | AAZ59246.1 | PMN2A_1724 | PMN2A_1758 | Dihydrouridine synthase TIM-barrel protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Fmu, rRNA SAM-dependent methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.472 |
| AAZ59212.1 | ABU23863.1 | PMN2A_1724 | PMN2A_1927 | Dihydrouridine synthase TIM-barrel protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Hypothetical protein; Alternative locus ID: NATL2_04251. | 0.572 |
| AAZ59212.1 | guaA | PMN2A_1724 | PMN2A_1363 | Dihydrouridine synthase TIM-barrel protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.473 |
| AAZ59212.1 | gyrB | PMN2A_1724 | PMN2A_1213 | Dihydrouridine synthase TIM-barrel protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.419 |
| AAZ59212.1 | panC/cmk | PMN2A_1724 | PMN2A_1165 | Dihydrouridine synthase TIM-barrel protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | 0.562 |
| AAZ59212.1 | pheT | PMN2A_1724 | PMN2A_0338 | Dihydrouridine synthase TIM-barrel protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | phenylalanyl-tRNA synthetase beta subunit; Alternative locus ID: NATL2_09581; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.472 |
| AAZ59212.1 | priA | PMN2A_1724 | PMN2A_1830 | Dihydrouridine synthase TIM-barrel protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Replication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.430 |
| AAZ59212.1 | truA | PMN2A_1724 | PMN2A_1104 | Dihydrouridine synthase TIM-barrel protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | tRNA pseudouridine synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.481 |
| AAZ59246.1 | AAZ59212.1 | PMN2A_1758 | PMN2A_1724 | Fmu, rRNA SAM-dependent methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Dihydrouridine synthase TIM-barrel protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.472 |
| AAZ59246.1 | pheT | PMN2A_1758 | PMN2A_0338 | Fmu, rRNA SAM-dependent methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | phenylalanyl-tRNA synthetase beta subunit; Alternative locus ID: NATL2_09581; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.701 |
| ABU23863.1 | AAZ59212.1 | PMN2A_1927 | PMN2A_1724 | Hypothetical protein; Alternative locus ID: NATL2_04251. | Dihydrouridine synthase TIM-barrel protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.572 |
| guaA | AAZ58821.1 | PMN2A_1363 | PMN2A_1332 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | DNA topoisomerase IV subunit A; Alternative locus ID: NATL2_00041. | 0.474 |
| guaA | AAZ59212.1 | PMN2A_1363 | PMN2A_1724 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Dihydrouridine synthase TIM-barrel protein nifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.473 |
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