close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAZ59305.1Exodeoxyribonuclease III; Alternative locus ID: NATL2_05231. (275 aa)    
Predicted Functional Partners:
nth
Endonuclease III/Nth; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
 0.965
polA
DNA polymerase A; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.903
AAZ58092.1
Ribosomal large subunit pseudouridine synthase F; Alternative locus ID: NATL2_13571; Belongs to the pseudouridine synthase RsuA family.
  
    0.821
AAZ58817.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.819
AAZ58695.1
A/G-specific DNA-adenine glycosylase; Alternative locus ID: NATL2_20271.
    
 0.817
AAZ59089.1
methylpurine-DNA glycosylase (MPG); Alternative locus ID: NATL2_02931; Belongs to the DNA glycosylase MPG family.
  
  
 0.687
AAZ58983.1
DNA polymerase III, delta prime subunit; Alternative locus ID: NATL2_01811.
   
  0.642
AAZ57635.1
Putative cytidine/deoxycytidylate deaminase; Alternative locus ID: NATL2_07571.
   
 
 0.595
AAZ59306.1
Hypothetical protein; Alternative locus ID: NATL2_05241.
       0.558
AAZ59307.1
Conserved hypothetical protein; Alternative locus ID: NATL2_05251.
       0.555
Your Current Organism:
Prochlorococcus marinus NATL2A
NCBI taxonomy Id: 59920
Other names: P. marinus str. NATL2A, Prochlorococcus marinus str. NATL2A, Prochlorococcus sp. NATL2A
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.