STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EU91_0331Citrate synthase (si); Alternative locus ID: PGP2_0653; Belongs to the citrate synthase family. (381 aa)    
Predicted Functional Partners:
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.986
EU91_1761
Isocitrate dehydrogenase (NADP); Alternative locus ID: PGP2_0363.
 
 0.986
EU91_1866
Aconitate hydratase 2; Alternative locus ID: PGP2_0468; Belongs to the aconitase/IPM isomerase family.
  
 
 0.985
EU91_0568
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Alternative locus ID: PGP2_0890.
  
 0.984
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.959
EU91_1679
Ferredoxin-dependent glutamate synthase; Alternative locus ID: PGP2_0280.
    
 0.954
mqo
Malate:quinone oxidoreductase; Alternative locus ID: PGP2_0910.
   
 
 0.952
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.942
EU91_0698
Aspartate aminotransferase; Alternative locus ID: PGP2_1004.
  
 0.930
EU91_0227
Biotin carboxylase of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
   
 
 0.927
Your Current Organism:
Prochlorococcus marinus GP2
NCBI taxonomy Id: 59925
Other names: P. marinus str. GP2, Prochlorococcus marinus str. GP2, Prochlorococcus marinus str. RCC296, Prochlorococcus sp. GP2, Prochlorococcus sp. RCC296
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.