Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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secDProtein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. (489 aa)    
Predicted Functional Partners:
EU91_0902
Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
 0.999
EU91_1274
Inner membrane protein translocase component YidC; Alternative locus ID: PGP2_1561; short form OxaI-like.
  
 0.966
secY
Preprotein translocase secY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
 0.942
secE
Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
   
 0.938
EU91_1679
Ferredoxin-dependent glutamate synthase; Alternative locus ID: PGP2_0280.
    
  0.924
pheT
Phenylalanyl-tRNA synthetase beta chain; Alternative locus ID: PGP2_1268; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
   
 
 0.848
secA
Protein export cytoplasm protein SecA ATPase RNA helicase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
  
 
 0.840
EU91_0900
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
       0.837
EU91_1600
Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
   
 0.765
EU91_0903
Hypothetical protein; Alternative locus ID: PGP2_1209; FIG00941199: hypothetical protein.
       0.751
Your Current Organism:
Prochlorococcus marinus GP2
NCBI taxonomy Id: 59925
Other names: P. marinus str. GP2, Prochlorococcus marinus str. GP2, Prochlorococcus marinus str. RCC296, Prochlorococcus sp. GP2, Prochlorococcus sp. RCC296
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