STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EV02_0712Exodeoxyribonuclease III; Alternative locus ID: PSB_0180. (245 aa)    
Predicted Functional Partners:
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
 0.992
polA
DNA polymerasee I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.968
EV02_1236
DNA polymerasee III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.957
EV02_1896
Ribosomal large subunit pseudouridine synthase F; Alternative locus ID: PSB_1365; Belongs to the pseudouridine synthase RsuA family.
  
    0.874
EV02_1273
ATP-dependent DNA ligase; Alternative locus ID: PSB_0741.
 
 
 0.821
EV02_0988
DNA-3-methyladenine glycosylase II; Alternative locus ID: PSB_0456; Belongs to the DNA glycosylase MPG family.
     
 0.796
EV02_0077
ATP-dependent DNA ligase LigC; Alternative locus ID: PSB_1474.
  
 
 0.791
EV02_0234
tRNA-specific adenosine-34 deaminase; Alternative locus ID: PSB_1631.
     
 0.736
EV02_0711
Hypothetical protein; Alternative locus ID: PSB_0179; FIG00941245: hypothetical protein.
       0.632
EV02_0710
Hypothetical protein; Alternative locus ID: PSB_0178; FIG00941087: hypothetical protein.
 
     0.620
Your Current Organism:
Prochlorococcus marinus SB
NCBI taxonomy Id: 59926
Other names: P. marinus str. SB, Prochlorococcus marinus str. RCC295, Prochlorococcus marinus str. SB, Prochlorococcus sp. RCC295, Prochlorococcus sp. SB
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.