STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menDMenaquinone biosynthesis protein; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. (575 aa)    
Predicted Functional Partners:
EAR17415.1
COG1169 Isochorismate synthase.
 
 0.983
menB
Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
 
  
 0.966
EAR20115.1
Esterase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
  
 
 0.890
EAR17418.1
Probable O-succinylbenzoic acid--CoA ligase (OSB-CoA synthetase); COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
   
 0.837
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Involved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4- naphthoquinone; Belongs to the MenA family. Type 2 subfamily.
 
   
 0.735
EAR17417.1
Putative O-succinylbenzoate synthase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
  
 0.733
EAR18531.1
COG1376 Uncharacterized protein conserved in bacteria.
       0.613
EAR18527.1
Hypothetical protein.
       0.582
EAR18528.1
COG0681 Signal peptidase I; Belongs to the peptidase S26 family.
       0.573
glgA
Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
     
 0.566
Your Current Organism:
Synechococcus sp. WH 7805
NCBI taxonomy Id: 59931
Other names: S. sp. WH 7805, Synechococcus WH7805, Synechococcus sp. (strain WH7805), Synechococcus sp. WH7805
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