STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metAAPutative homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (297 aa)    
Predicted Functional Partners:
EAR18923.1
COG2873 O-acetylhomoserine sulfhydrylase.
 
 
 0.971
EAR17451.1
Hypothetical protein; COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
  
 0.895
EAR18685.1
Putative methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.845
EAR18361.1
COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
 
 
 0.844
EAR18090.1
Homoserine dehydrogenase:ACT domain; COG0460 Homoserine dehydrogenase.
  
 
 0.839
hisI
Histidine biosynthesis bifunctional protein HisIE; COG0139 Phosphoribosyl-AMP cyclohydrolase; In the N-terminal section; belongs to the PRA-CH family.
  
    0.746
EAR18925.1
Hypothetical protein.
       0.714
rpmE
50S ribosomal protein L31; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
   
    0.698
EAR18362.1
COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
 
 
 0.690
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
  
 0.592
Your Current Organism:
Synechococcus sp. WH 7805
NCBI taxonomy Id: 59931
Other names: S. sp. WH 7805, Synechococcus WH7805, Synechococcus sp. (strain WH7805), Synechococcus sp. WH7805
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