STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAR18271.1Carboxymethylenebutenolidase; COG5485 Predicted ester cyclase. (187 aa)    
Predicted Functional Partners:
EAR17364.1
Hypothetical protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.
  
  
 0.650
EAR17650.1
COG5031 Uncharacterized protein involved in ubiquinone biosynthesis.
  
     0.540
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
    0.532
EAR17273.1
COG0412 Dienelactone hydrolase and related enzymes.
  
  
  0.516
cobD
Putative cobalamin biosynthetic protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
       0.472
EAR18432.1
COG2343 Uncharacterized protein conserved in bacteria.
  
     0.444
EAR17596.1
Hypothetical protein; COG0277 FAD/FMN-containing dehydrogenases.
  
     0.427
EAR18197.1
Putative oxidoreductase; COG1231 Monoamine oxidase.
  
     0.414
EAR17367.1
COG0477 Permeases of the major facilitator superfamily.
  
     0.411
EAR17314.1
COG5031 Uncharacterized protein involved in ubiquinone biosynthesis.
  
     0.401
Your Current Organism:
Synechococcus sp. WH 7805
NCBI taxonomy Id: 59931
Other names: S. sp. WH 7805, Synechococcus WH7805, Synechococcus sp. (strain WH7805), Synechococcus sp. WH7805
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