STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobSCobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (270 aa)    
Predicted Functional Partners:
EAR19125.1
cbiH protein and precorrin-3B C17-methyltransferase; COG2073 Cobalamin biosynthesis protein CbiG.
 
  
 0.994
EAR20057.1
Possible cob(I)alamin adenosyltransferase; COG2109 ATP:corrinoid adenosyltransferase.
 
 
 0.964
EAR19197.1
COG2109 ATP:corrinoid adenosyltransferase.
 
 
 0.950
EAR18849.1
COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase.
 
 
 0.934
EAR19063.1
cob(I)yrinic acid a,c-diamide adenosyltransferase; COG2109 ATP:corrinoid adenosyltransferase.
 
 
 0.931
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.917
EAR18203.1
Putative precorrin-6y methylase; COG2241 Precorrin-6B methylase 1.
 
  
 0.881
EAR19967.1
Putative precorrin-4 c11-methyltransferase; COG2875 Precorrin-4 methylase; Belongs to the precorrin methyltransferase family.
 
 
 0.858
cobD
Putative cobalamin biosynthetic protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.857
EAR18390.1
COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family.
 
  
 0.853
Your Current Organism:
Synechococcus sp. WH 7805
NCBI taxonomy Id: 59931
Other names: S. sp. WH 7805, Synechococcus WH7805, Synechococcus sp. (strain WH7805), Synechococcus sp. WH7805
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