STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaXDNA polymerase, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (587 aa)    
Predicted Functional Partners:
EAR18576.1
COG0587 DNA polymerase III, alpha subunit.
   
 0.999
EAR17299.1
Hypothetical protein; COG1466 DNA polymerase III, delta subunit.
   
 0.999
EAR17741.1
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.999
EAR19472.1
DNA polymerase III subunit delta; COG0470 ATPase involved in DNA replication.
 
 
0.999
EAR18558.1
Exonuclease; COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.
   
 0.980
EAR19415.1
COG0629 Single-stranded DNA-binding protein.
    
 
 0.927
EAR20033.1
Hypothetical protein; COG0629 Single-stranded DNA-binding protein.
    
 
 0.927
EAR18922.1
Hypothetical protein.
   
 0.894
EAR17889.1
Replicative DNA helicase DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
   
 
 0.877
EAR17677.1
COG1219 ATP-dependent protease Clp, ATPase subunit; Belongs to the ClpX chaperone family.
  
  
 0.766
Your Current Organism:
Synechococcus sp. WH 7805
NCBI taxonomy Id: 59931
Other names: S. sp. WH 7805, Synechococcus WH7805, Synechococcus sp. (strain WH7805), Synechococcus sp. WH7805
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