STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAR19555.1Putative ATPase, AAA family protein; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase. (759 aa)    
Predicted Functional Partners:
EAR18969.1
Hypothetical protein; COG0514 Superfamily II DNA helicase.
    
 
 0.850
EAR17741.1
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 
 0.774
EAR17657.1
Putative ATP-dependent helicase; COG0553 Superfamily II DNA/RNA helicases, SNF2 family.
 
 
 
 0.654
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
  
 0.611
EAR19556.1
COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.560
EAR19557.1
Putative RND family multidrug efflux transporter; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.545
EAR19558.1
Hypothetical protein; COG0477 Permeases of the major facilitator superfamily.
       0.545
nadE
Carbon-nitrogen hydrolase:NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
    0.530
EAR19215.1
CinA-like protein; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family.
     
 0.478
guaA
Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.
     
 0.459
Your Current Organism:
Synechococcus sp. WH 7805
NCBI taxonomy Id: 59931
Other names: S. sp. WH 7805, Synechococcus WH7805, Synechococcus sp. (strain WH7805), Synechococcus sp. WH7805
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