STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FIBRA_03372Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (338 aa)    
Predicted Functional Partners:
FIBRA_02704
Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
   
 0.999
FIBRA_08097
WAPL domain-containing protein.
   
 0.999
FIBRA_00171
Uncharacterized protein; Belongs to the actin family.
  
0.999
FIBRA_06884
Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
   
 0.998
FIBRA_01858
Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.
   
 0.998
FIBRA_06610
WD_REPEATS_REGION domain-containing protein.
   
 0.998
FIBRA_07839
Uncharacterized protein.
    
 0.991
FIBRA_06672
DUF2013 domain-containing protein.
    
 0.976
FIBRA_04050
Uncharacterized protein; Belongs to the actin family.
  
 
0.967
FIBRA_05357
Uncharacterized protein.
  
 
0.967
Your Current Organism:
Fibroporia radiculosa
NCBI taxonomy Id: 599839
Other names: Antrodia radiculosa, F. radiculosa
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.