node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FIBRA_01167 | FIBRA_02799 | J4HSV6 | J4H220 | Uncharacterized protein. | Uncharacterized protein. | 0.960 |
FIBRA_01167 | FIBRA_03216 | J4HSV6 | J4G4L2 | Uncharacterized protein. | RRM domain-containing protein. | 0.902 |
FIBRA_01167 | NCS6 | J4HSV6 | J4H3Y2 | Uncharacterized protein. | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. | 0.830 |
FIBRA_01167 | SPB1 | J4HSV6 | J4I889 | Uncharacterized protein. | AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. | 0.991 |
FIBRA_01648 | FIBRA_02799 | J4G138 | J4H220 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | Uncharacterized protein. | 0.443 |
FIBRA_01648 | FIBRA_06878 | J4G138 | J4HZT0 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | Rhodanese domain-containing protein. | 0.755 |
FIBRA_01648 | NCS6 | J4G138 | J4H3Y2 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. | 0.756 |
FIBRA_01648 | SPB1 | J4G138 | J4I889 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. | 0.469 |
FIBRA_02799 | FIBRA_01167 | J4H220 | J4HSV6 | Uncharacterized protein. | Uncharacterized protein. | 0.960 |
FIBRA_02799 | FIBRA_01648 | J4H220 | J4G138 | Uncharacterized protein. | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | 0.443 |
FIBRA_02799 | FIBRA_03216 | J4H220 | J4G4L2 | Uncharacterized protein. | RRM domain-containing protein. | 0.949 |
FIBRA_02799 | NCS6 | J4H220 | J4H3Y2 | Uncharacterized protein. | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. | 0.819 |
FIBRA_02799 | SPB1 | J4H220 | J4I889 | Uncharacterized protein. | AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. | 0.951 |
FIBRA_03216 | FIBRA_01167 | J4G4L2 | J4HSV6 | RRM domain-containing protein. | Uncharacterized protein. | 0.902 |
FIBRA_03216 | FIBRA_02799 | J4G4L2 | J4H220 | RRM domain-containing protein. | Uncharacterized protein. | 0.949 |
FIBRA_03216 | NCS6 | J4G4L2 | J4H3Y2 | RRM domain-containing protein. | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. | 0.775 |
FIBRA_03216 | SPB1 | J4G4L2 | J4I889 | RRM domain-containing protein. | AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. | 0.957 |
FIBRA_03797 | FIBRA_05355 | J4I9T7 | J4GQU7 | Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.553 |
FIBRA_03797 | FIBRA_06534 | J4I9T7 | J4HZ95 | Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. | Glutamine amidotransferase type-1 domain-containing protein. | 0.895 |
FIBRA_03797 | NCS6 | J4I9T7 | J4H3Y2 | Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. | 0.744 |