| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BPLAN_014 | BPLAN_015 | BPLAN_014 | BPLAN_015 | Putative translation initiation inhibitor; COG0251; Protein involved in mRNA catabolic process. | Conserved hypothetical protein; COG1452. | 0.786 |
| BPLAN_014 | folK | BPLAN_014 | BPLAN_016 | Putative translation initiation inhibitor; COG0251; Protein involved in mRNA catabolic process. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine; COG0801. | 0.559 |
| BPLAN_014 | mreB | BPLAN_014 | BPLAN_017 | Putative translation initiation inhibitor; COG0251; Protein involved in mRNA catabolic process. | Putative rod shape-determining protein MreB; COG1077; Protein involved in regulation of cell shape. | 0.408 |
| BPLAN_014 | mreC | BPLAN_014 | BPLAN_018 | Putative translation initiation inhibitor; COG0251; Protein involved in mRNA catabolic process. | Putative rod shape-determining protein MreC; COG1792. | 0.402 |
| BPLAN_014 | ribD | BPLAN_014 | BPLAN_491 | Putative translation initiation inhibitor; COG0251; Protein involved in mRNA catabolic process. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.474 |
| BPLAN_015 | BPLAN_014 | BPLAN_015 | BPLAN_014 | Conserved hypothetical protein; COG1452. | Putative translation initiation inhibitor; COG0251; Protein involved in mRNA catabolic process. | 0.786 |
| BPLAN_015 | folK | BPLAN_015 | BPLAN_016 | Conserved hypothetical protein; COG1452. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine; COG0801. | 0.550 |
| BPLAN_015 | mrdB | BPLAN_015 | BPLAN_021 | Conserved hypothetical protein; COG1452. | Cell cycle protein; COG0772; Protein involved in regulation of cell shape; Belongs to the SEDS family. | 0.458 |
| BPLAN_015 | mreB | BPLAN_015 | BPLAN_017 | Conserved hypothetical protein; COG1452. | Putative rod shape-determining protein MreB; COG1077; Protein involved in regulation of cell shape. | 0.410 |
| BPLAN_015 | mreC | BPLAN_015 | BPLAN_018 | Conserved hypothetical protein; COG1452. | Putative rod shape-determining protein MreC; COG1792. | 0.592 |
| folB | folC | BPLAN_348 | BPLAN_453 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Putative folylpolyglutamate synthase; COG0285; Protein involved in tetrahydrofolate biosynthetic process; Belongs to the folylpolyglutamate synthase family. | 0.452 |
| folB | folE | BPLAN_348 | BPLAN_070 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase I; COG0302; Protein involved in tetrahydrofolate biosynthetic process. | 0.940 |
| folB | folK | BPLAN_348 | BPLAN_016 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine; COG0801. | 0.974 |
| folB | folP | BPLAN_348 | BPLAN_533 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.993 |
| folB | ribD | BPLAN_348 | BPLAN_491 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.558 |
| folC | folB | BPLAN_453 | BPLAN_348 | Putative folylpolyglutamate synthase; COG0285; Protein involved in tetrahydrofolate biosynthetic process; Belongs to the folylpolyglutamate synthase family. | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.452 |
| folC | folE | BPLAN_453 | BPLAN_070 | Putative folylpolyglutamate synthase; COG0285; Protein involved in tetrahydrofolate biosynthetic process; Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase I; COG0302; Protein involved in tetrahydrofolate biosynthetic process. | 0.452 |
| folC | folK | BPLAN_453 | BPLAN_016 | Putative folylpolyglutamate synthase; COG0285; Protein involved in tetrahydrofolate biosynthetic process; Belongs to the folylpolyglutamate synthase family. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine; COG0801. | 0.749 |
| folC | folP | BPLAN_453 | BPLAN_533 | Putative folylpolyglutamate synthase; COG0285; Protein involved in tetrahydrofolate biosynthetic process; Belongs to the folylpolyglutamate synthase family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.995 |
| folC | ribD | BPLAN_453 | BPLAN_491 | Putative folylpolyglutamate synthase; COG0285; Protein involved in tetrahydrofolate biosynthetic process; Belongs to the folylpolyglutamate synthase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.487 |