Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mreBPutative rod shape-determining protein MreB; COG1077; Protein involved in regulation of cell shape. (345 aa)    
Predicted Functional Partners:
mreC
Putative rod shape-determining protein MreC; COG1792.
  
 
 0.963
mrdA
Putative penicillin-binding protein 2; COG0768; Protein involved in peptidoglycan biosynthetic process.
 
 
 
 0.930
mrdB
Cell cycle protein; COG0772; Protein involved in regulation of cell shape; Belongs to the SEDS family.
 
 
 0.913
BPLAN_019
Conserved hypothetical protein.
       0.767
secD
Bifunctional-export transmembrane SecDF protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
    0.623
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.617
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine; COG0801.
       0.558
prsA
Ribose-phosphate pyrophosphokinase; COG0462; Protein involved in purine ribonucleotide biosynthetic process.
   
    0.521
lpxC
UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
     
 0.499
BPLAN_063
Conserved hypothetical protein.
    
 
 0.498
Your Current Organism:
Blattabacterium sp. BPLAN
NCBI taxonomy Id: 600809
Other names: B. sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) strain BPLAN
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.