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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (309 aa)    
Predicted Functional Partners:
maeB
Putative NADP-dependent malic enzyme; COG0281; Protein involved in phosphate acetyltransferase activity.
  
 0.969
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.952
aspC
Aspartate aminotransferase; COG0436.
  
 0.917
pck
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
  
 
 0.916
gcvP
COG1003; Protein involved in glycine decarboxylation via glycine cleavage system; Belongs to the GcvP family.
  
  
 0.862
sad
Succinate-semialdehyde dehydrogenase; COG1012; Protein involved in oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor.
   
 0.846
gdhA
Glutamate dehydrogenase; COG0334; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.841
purB
Adenylosuccinate lyase; COG0015; Protein involved in purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
 0.835
argH
Argininosuccinate lyase; COG0165; Protein involved in arginine biosynthetic process via ornithine.
   
  0.832
gapA
COG0057; Protein involved in glyceraldehyde-3-phosphate metabolic process; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.691
Your Current Organism:
Blattabacterium sp. BPLAN
NCBI taxonomy Id: 600809
Other names: B. sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) strain BPLAN
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