STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nthEndonuclease III; COG0177; Protein involved in DNA repair. (213 aa)    
Predicted Functional Partners:
xthA
Exodeoxyribonuclease III; COG0708.
 
 0.962
BPLAN_051
ATP-dependent Clp protease, ATP-binding subunit; COG0542; Protein involved in ATPase activity, coupled; Belongs to the ClpA/ClpB family.
       0.752
dnaX
DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
       0.540
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
    0.536
dnaE
DNA-directed DNA polymerase; COG0587.
  
  
 0.506
pyrE
Bifunctional orotate phosphoribosyltransferase/orotidine 5'-phosphate decarboxylase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
     
 0.451
hisB
Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; COG0131; Protein involved in histidinol-phosphatase activity; Belongs to the imidazoleglycerol-phosphate dehydratase family. In the N-terminal section; belongs to the histidinol- phosphatase family.
   
 
 0.402
polA
DNA polymerase I; COG0258.
  
 
 0.401
Your Current Organism:
Blattabacterium sp. BPLAN
NCBI taxonomy Id: 600809
Other names: B. sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) strain BPLAN
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