STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metBCystathionine gamma-synthase; COG0626; Protein involved in acetate biosynthetic process. (383 aa)    
Predicted Functional Partners:
cysK
Cysteine synthase A; COG0031; Protein involved in cysteine biosynthetic process from serine; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.975
thrA
Aspartokinase/homoserine dehydrogenase; COG0527.
  
 
 0.954
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.920
ilvE
COG0115; Protein involved in branched chain family amino acid biosynthetic process.
   
 0.918
cysJ
Sulfite reductase; COG0369.
  
 
 0.915
aspC
Aspartate aminotransferase; COG0436.
  
 
 0.913
cysE
COG1045; Protein involved in serine O-acetyltransferase activity.
  
 
 0.871
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.857
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
 
 0.845
metF
5,10-methylenetetrahydrofolate reductase; COG0685; Protein involved in methionine biosynthetic process; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.729
Your Current Organism:
Blattabacterium sp. BPLAN
NCBI taxonomy Id: 600809
Other names: B. sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) strain BPLAN
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