pyrE protein (Blattabacterium sp. BPLAN) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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Assay-based Predictions

experimentally determined

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Your Current Organism:

Blattabacterium sp. BPLAN

NCBI taxonomy Id: 600809
Other names: B. sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) strain BPLAN

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
carA	carB	BPLAN_324	BPLAN_323	Carbamoyl phosphate synthase small subunit; COG0505; Protein involved in pyrimidine ribonucleotide biosynthetic process; Belongs to the CarA family.	Carbamoyl-phosphate synthase large subunit; COG0458; Protein involved in pyrimidine ribonucleotide biosynthetic process.	0.999
carA	guaA	BPLAN_324	BPLAN_161	Carbamoyl phosphate synthase small subunit; COG0505; Protein involved in pyrimidine ribonucleotide biosynthetic process; Belongs to the CarA family.	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	0.400
carA	purL	BPLAN_324	BPLAN_153	Carbamoyl phosphate synthase small subunit; COG0505; Protein involved in pyrimidine ribonucleotide biosynthetic process; Belongs to the CarA family.	Phosphoribosylformylglycinamidine synthase; COG0046; Protein involved in 'de novo' IMP biosynthetic process.	0.910
carA	pyrD	BPLAN_324	BPLAN_127	Carbamoyl phosphate synthase small subunit; COG0505; Protein involved in pyrimidine ribonucleotide biosynthetic process; Belongs to the CarA family.	Dihydroorotate dehydrogenase 1A; Catalyzes the conversion of dihydroorotate to orotate.	0.919
carA	pyrE	BPLAN_324	BPLAN_128	Carbamoyl phosphate synthase small subunit; COG0505; Protein involved in pyrimidine ribonucleotide biosynthetic process; Belongs to the CarA family.	Bifunctional orotate phosphoribosyltransferase/orotidine 5'-phosphate decarboxylase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).	0.995
carB	carA	BPLAN_323	BPLAN_324	Carbamoyl-phosphate synthase large subunit; COG0458; Protein involved in pyrimidine ribonucleotide biosynthetic process.	Carbamoyl phosphate synthase small subunit; COG0505; Protein involved in pyrimidine ribonucleotide biosynthetic process; Belongs to the CarA family.	0.999
carB	guaA	BPLAN_323	BPLAN_161	Carbamoyl-phosphate synthase large subunit; COG0458; Protein involved in pyrimidine ribonucleotide biosynthetic process.	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	0.805
carB	purL	BPLAN_323	BPLAN_153	Carbamoyl-phosphate synthase large subunit; COG0458; Protein involved in pyrimidine ribonucleotide biosynthetic process.	Phosphoribosylformylglycinamidine synthase; COG0046; Protein involved in 'de novo' IMP biosynthetic process.	0.632
carB	pyrD	BPLAN_323	BPLAN_127	Carbamoyl-phosphate synthase large subunit; COG0458; Protein involved in pyrimidine ribonucleotide biosynthetic process.	Dihydroorotate dehydrogenase 1A; Catalyzes the conversion of dihydroorotate to orotate.	0.970
carB	pyrE	BPLAN_323	BPLAN_128	Carbamoyl-phosphate synthase large subunit; COG0458; Protein involved in pyrimidine ribonucleotide biosynthetic process.	Bifunctional orotate phosphoribosyltransferase/orotidine 5'-phosphate decarboxylase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).	0.996
carB	thrA	BPLAN_323	BPLAN_138	Carbamoyl-phosphate synthase large subunit; COG0458; Protein involved in pyrimidine ribonucleotide biosynthetic process.	Aspartokinase/homoserine dehydrogenase; COG0527.	0.406
cmk	guaA	BPLAN_575	BPLAN_161	Cytidylate kinase; COG0283; Protein involved in nucleobase, nucleoside and nucleotide interconversion.	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	0.470
cmk	purL	BPLAN_575	BPLAN_153	Cytidylate kinase; COG0283; Protein involved in nucleobase, nucleoside and nucleotide interconversion.	Phosphoribosylformylglycinamidine synthase; COG0046; Protein involved in 'de novo' IMP biosynthetic process.	0.483
cmk	pyrE	BPLAN_575	BPLAN_128	Cytidylate kinase; COG0283; Protein involved in nucleobase, nucleoside and nucleotide interconversion.	Bifunctional orotate phosphoribosyltransferase/orotidine 5'-phosphate decarboxylase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).	0.797
cmk	surE	BPLAN_575	BPLAN_149	Cytidylate kinase; COG0283; Protein involved in nucleobase, nucleoside and nucleotide interconversion.	Acid phosphatase, survival protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.910
guaA	carA	BPLAN_161	BPLAN_324	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	Carbamoyl phosphate synthase small subunit; COG0505; Protein involved in pyrimidine ribonucleotide biosynthetic process; Belongs to the CarA family.	0.400
guaA	carB	BPLAN_161	BPLAN_323	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	Carbamoyl-phosphate synthase large subunit; COG0458; Protein involved in pyrimidine ribonucleotide biosynthetic process.	0.805
guaA	cmk	BPLAN_161	BPLAN_575	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	Cytidylate kinase; COG0283; Protein involved in nucleobase, nucleoside and nucleotide interconversion.	0.470
guaA	prsA	BPLAN_161	BPLAN_142	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	Ribose-phosphate pyrophosphokinase; COG0462; Protein involved in purine ribonucleotide biosynthetic process.	0.719
guaA	purL	BPLAN_161	BPLAN_153	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylformylglycinamidine synthase; COG0046; Protein involved in 'de novo' IMP biosynthetic process.	0.991

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