purM protein (Blattabacterium sp. BPLAN) - STRING interaction network

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purM

Phosphoribosylaminoimidazole synthetase; COG0150; Protein involved in purine ribonucleotide biosynthetic process. (328 aa)

Predicted Functional Partners:

purL

0.999

purD

0.999

purF

0.998

purN

0.998

purC

0.995

purB

0.991

purE

0.980

purH

0.973

guaA

0.839

guaB

0.830

Your Current Organism:

Blattabacterium sp. BPLAN

NCBI taxonomy Id: 600809
Other names: B. sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) strain BPLAN

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
guaA	guaB	BPLAN_161	BPLAN_474	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.999
guaA	purB	BPLAN_161	BPLAN_152	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	Adenylosuccinate lyase; COG0015; Protein involved in purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.872
guaA	purC	BPLAN_161	BPLAN_155	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylamidoimidazole-succinocarboxamide synthase; COG0152; Protein involved in purine ribonucleotide biosynthetic process; Belongs to the SAICAR synthetase family.	0.804
guaA	purD	BPLAN_161	BPLAN_160	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylamine--glycine ligase; COG0151; Protein involved in purine ribonucleotide biosynthetic process; Belongs to the GARS family.	0.939
guaA	purE	BPLAN_161	BPLAN_154	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).	0.731
guaA	purF	BPLAN_161	BPLAN_156	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.	0.880
guaA	purH	BPLAN_161	BPLAN_159	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylaminoimidazole carboxamide formyltransferase/IMP cyclohydrolase; COG0138; Protein involved in purine ribonucleotide biosynthetic process.	0.953
guaA	purL	BPLAN_161	BPLAN_153	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylformylglycinamidine synthase; COG0046; Protein involved in 'de novo' IMP biosynthetic process.	0.991
guaA	purM	BPLAN_161	BPLAN_157	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylaminoimidazole synthetase; COG0150; Protein involved in purine ribonucleotide biosynthetic process.	0.839
guaA	purN	BPLAN_161	BPLAN_158	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylglycinamide formyltransferase; COG0299.	0.827
guaB	guaA	BPLAN_474	BPLAN_161	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.	0.999
guaB	purB	BPLAN_474	BPLAN_152	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Adenylosuccinate lyase; COG0015; Protein involved in purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.801
guaB	purC	BPLAN_474	BPLAN_155	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Phosphoribosylamidoimidazole-succinocarboxamide synthase; COG0152; Protein involved in purine ribonucleotide biosynthetic process; Belongs to the SAICAR synthetase family.	0.699
guaB	purD	BPLAN_474	BPLAN_160	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Phosphoribosylamine--glycine ligase; COG0151; Protein involved in purine ribonucleotide biosynthetic process; Belongs to the GARS family.	0.694
guaB	purE	BPLAN_474	BPLAN_154	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).	0.688
guaB	purF	BPLAN_474	BPLAN_156	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.	0.838
guaB	purH	BPLAN_474	BPLAN_159	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Phosphoribosylaminoimidazole carboxamide formyltransferase/IMP cyclohydrolase; COG0138; Protein involved in purine ribonucleotide biosynthetic process.	0.993
guaB	purL	BPLAN_474	BPLAN_153	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Phosphoribosylformylglycinamidine synthase; COG0046; Protein involved in 'de novo' IMP biosynthetic process.	0.871
guaB	purM	BPLAN_474	BPLAN_157	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Phosphoribosylaminoimidazole synthetase; COG0150; Protein involved in purine ribonucleotide biosynthetic process.	0.830
guaB	purN	BPLAN_474	BPLAN_158	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Phosphoribosylglycinamide formyltransferase; COG0299.	0.639

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