Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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purDPhosphoribosylamine--glycine ligase; COG0151; Protein involved in purine ribonucleotide biosynthetic process; Belongs to the GARS family. (411 aa)    
Predicted Functional Partners:
purL
Phosphoribosylformylglycinamidine synthase; COG0046; Protein involved in 'de novo' IMP biosynthetic process.
  
 0.999
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
 
 0.999
purM
Phosphoribosylaminoimidazole synthetase; COG0150; Protein involved in purine ribonucleotide biosynthetic process.
  
 0.999
purN
Phosphoribosylglycinamide formyltransferase; COG0299.
 
 0.999
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
 0.998
purC
Phosphoribosylamidoimidazole-succinocarboxamide synthase; COG0152; Protein involved in purine ribonucleotide biosynthetic process; Belongs to the SAICAR synthetase family.
  
 
 0.993
purH
Phosphoribosylaminoimidazole carboxamide formyltransferase/IMP cyclohydrolase; COG0138; Protein involved in purine ribonucleotide biosynthetic process.
  
 
 0.986
purB
Adenylosuccinate lyase; COG0015; Protein involved in purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 
 0.980
gcvP
COG1003; Protein involved in glycine decarboxylation via glycine cleavage system; Belongs to the GcvP family.
   
  
 0.953
guaA
Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.939
Your Current Organism:
Blattabacterium sp. BPLAN
NCBI taxonomy Id: 600809
Other names: B. sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) strain BPLAN
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