Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
BPLAN_169Thioredoxin; COG0526. (184 aa)    
Predicted Functional Partners:
ahpC
Alkyl hydroperoxide reductase, subunit C; COG0450; Protein involved in peroxiredoxin activity.
  
 0.926
dnaK
dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.901
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
    
 0.898
htpG
Heat shock protein 90; COG0326.
   
 0.822
pgk
Phosphoglycerate kinase; COG0126; Belongs to the phosphoglycerate kinase family.
 
 
 
 0.779
lpdA
COG1249; Protein involved in dihydrolipoamide metabolic process.
   
 0.771
lpdA-2
COG1249; Protein involved in dihydrolipoamide metabolic process.
   
 0.771
trxB
Thioredoxin reductase; COG0492; Protein involved in oxidation reduction.
  
 
 0.770
BPLAN_167
Conserved hypothetical protein; COG3323; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
   
   0.726
BPLAN_168
Conserved hypothetical protein; COG1579.
       0.686
Your Current Organism:
Blattabacterium sp. BPLAN
NCBI taxonomy Id: 600809
Other names: B. sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) strain BPLAN
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