Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
serSserine-tRNA synthetase; COG0172; Protein involved in seryl-tRNA aminoacylation. (424 aa)    
Predicted Functional Partners:
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
   0.820
metF
5,10-methylenetetrahydrofolate reductase; COG0685; Protein involved in methionine biosynthetic process; Belongs to the methylenetetrahydrofolate reductase family.
     
 0.781
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
 
 0.737
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
  
  
 0.710
argS
COG0018; Protein involved in arginyl-tRNA aminoacylation.
 
 
 0.687
folD
Putative methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
 
 0.685
cysS
COG0215; Protein involved in cysteinyl-tRNA aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.683
lysS
COG1190; Protein involved in lysyl-tRNA aminoacylation; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
 0.673
BPLAN_615
Conserved hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
  
    0.593
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
  
 0.588
Your Current Organism:
Blattabacterium sp. BPLAN
NCBI taxonomy Id: 600809
Other names: B. sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) strain BPLAN
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