Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
aspCAspartate aminotransferase; COG0436. (395 aa)    
Predicted Functional Partners:
pheA
Prephenate dehydratase; COG0077.
 
 
  0.989
thrA
Aspartokinase/homoserine dehydrogenase; COG0527.
  
 0.929
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.922
hisC
COG0079; Protein involved in histidinol-phosphate transaminase activity; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
 
 
0.915
BPLAN_327
Argininosuccinate synthase(argG)/acetyltransferase activity of N-acetylglutamate synthase (argA); COG0137; Protein involved in arginine biosynthetic process via ornithine.
   
 0.915
metB
Cystathionine gamma-synthase; COG0626; Protein involved in acetate biosynthetic process.
  
 
 0.912
tyrA
Prephenate dehydrogenase; COG0287.
  
 
 0.908
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
   
 0.905
gdhA
Glutamate dehydrogenase; COG0334; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.905
cysK
Cysteine synthase A; COG0031; Protein involved in cysteine biosynthetic process from serine; Belongs to the cysteine synthase/cystathionine beta- synthase family.
     
 0.904
Your Current Organism:
Blattabacterium sp. BPLAN
NCBI taxonomy Id: 600809
Other names: B. sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) strain BPLAN
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