| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BPLAN_316 | BPLAN_317 | BPLAN_316 | BPLAN_317 | Conserved hypothetical protein; COG0795. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | 0.690 |
| BPLAN_316 | ftsK | BPLAN_316 | BPLAN_315 | Conserved hypothetical protein; COG0795. | DNA translocase; COG1674; Belongs to the FtsK/SpoIIIE/SftA family. | 0.558 |
| BPLAN_317 | BPLAN_316 | BPLAN_317 | BPLAN_316 | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | Conserved hypothetical protein; COG0795. | 0.690 |
| BPLAN_317 | ftsK | BPLAN_317 | BPLAN_315 | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | DNA translocase; COG1674; Belongs to the FtsK/SpoIIIE/SftA family. | 0.525 |
| BPLAN_317 | guaA | BPLAN_317 | BPLAN_161 | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.412 |
| BPLAN_317 | guaB | BPLAN_317 | BPLAN_474 | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.646 |
| BPLAN_317 | pyrE | BPLAN_317 | BPLAN_128 | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | Bifunctional orotate phosphoribosyltransferase/orotidine 5'-phosphate decarboxylase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.414 |
| BPLAN_317 | ribC | BPLAN_317 | BPLAN_558 | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | Riboflavin synthase subunit alpha; COG0307; Protein involved in riboflavin biosynthetic process. | 0.996 |
| BPLAN_317 | ribD | BPLAN_317 | BPLAN_491 | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.996 |
| BPLAN_317 | ribE | BPLAN_317 | BPLAN_094 | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | Riboflavin synthase subunit beta; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.996 |
| ftsK | BPLAN_316 | BPLAN_315 | BPLAN_316 | DNA translocase; COG1674; Belongs to the FtsK/SpoIIIE/SftA family. | Conserved hypothetical protein; COG0795. | 0.558 |
| ftsK | BPLAN_317 | BPLAN_315 | BPLAN_317 | DNA translocase; COG1674; Belongs to the FtsK/SpoIIIE/SftA family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | 0.525 |
| guaA | BPLAN_317 | BPLAN_161 | BPLAN_317 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | 0.412 |
| guaA | guaB | BPLAN_161 | BPLAN_474 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
| guaA | pyrE | BPLAN_161 | BPLAN_128 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Bifunctional orotate phosphoribosyltransferase/orotidine 5'-phosphate decarboxylase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.791 |
| guaA | ribD | BPLAN_161 | BPLAN_491 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.643 |
| guaB | BPLAN_317 | BPLAN_474 | BPLAN_317 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | 0.646 |
| guaB | guaA | BPLAN_474 | BPLAN_161 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.999 |
| guaB | pyrE | BPLAN_474 | BPLAN_128 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Bifunctional orotate phosphoribosyltransferase/orotidine 5'-phosphate decarboxylase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.722 |
| guaB | ribD | BPLAN_474 | BPLAN_491 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.708 |
