Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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gene co-occurrence
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nrdERibonucleotide-diphosphate reductase subunit alpha; COG0209; Protein involved in class I ribonucleotide reductase activity. (571 aa)    
Predicted Functional Partners:
gmk
Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP.
  
  
 0.913
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
    
 0.913
cmk
Cytidylate kinase; COG0283; Protein involved in nucleobase, nucleoside and nucleotide interconversion.
   
 
 0.910
ndk
Nucleoside-diphosphate kinase; COG0105.
     
 0.907
trxA
Thioredoxin; COG0526; Protein involved in oxidation reduction; Belongs to the thioredoxin family.
  
 
 0.797
rpsA
30S ribosomal protein S1; COG0539.
  
    0.784
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.743
dnaN
DNA polymerase III, beta subunit; COG0592.
   
 
 0.647
BPLAN_169
Thioredoxin; COG0526.
   
 0.611
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; COG0756.
  
  
 0.588
Your Current Organism:
Blattabacterium sp. BPLAN
NCBI taxonomy Id: 600809
Other names: B. sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) str. BPLAN, Blattabacterium sp. (Periplaneta americana) strain BPLAN
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